Pharmacokinetic-pharmacodynamic modelling of QT interval prolongation following citalopram overdoses (Q35827376)

10 August 2017

Pharmacokinetic-pharmacodynamic modelling of QT interval prolongation following citalopram overdoses (English)

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10 August 2017

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2

Geoffrey K Isbister

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10 August 2017

3

Stephen B Duffull

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10 August 2017

1

Lena E Friberg

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PMCID

1884996

10 August 2017

language of work or name

English

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publication date

1 February 2006

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British Journal of Clinical Pharmacology

10 August 2017

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10 August 2017

61

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10 August 2017

177-190

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10 August 2017

2

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Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation

10 August 2017

1 reference

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Errors and misconceptions in ECG measurement used for the detection of drug induced QT interval prolongation

27 July 2018

1 reference

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Relative toxicity of selective serotonin reuptake inhibitors (SSRIs) in overdose

27 July 2018

1 reference

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Drug-induced torsades de pointes and implications for drug development.

27 July 2018

1 reference

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The impact of drug-induced QT interval prolongation on drug discovery and development

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1 reference

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Citalopram in fatal poisoning cases

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The role of activated charcoal and gastric emptying in gastrointestinal decontamination: a state-of-the-art review

27 July 2018

1 reference

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Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval

27 July 2018

1 reference

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The QT interval and torsade de pointes

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1 reference

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Long QT syndromes and torsade de pointes

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1 reference

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Pharmacokinetic interaction study of citalopram and cimetidine in healthy subjects.

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1 reference

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QT interval change with age in an overtly healthy older population.

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1 reference

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Fatal overdose with citalopram.

27 July 2018

1 reference

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Measurement of the QT interval and the risk associated with QTc interval prolongation: a review

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1 reference

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Multiple-dose activated charcoal and enhancement of systemic drug clearance: summary of studies in animals and human volunteers.

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The effect of quinidine and its metabolites on the electrocardiogram and systolic time intervals: concentration--effect relationships.

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Citalopram overdose: late presentation of torsades de pointes (TdP) with cardiac arrest

27 July 2018

1 reference

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The population pharmacokinetics of citalopram after deliberate self-poisoning: a Bayesian approach

24 September 2018

1 reference

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Analysis of population pharmacokinetic data using NONMEM and WinBUGS.

24 September 2018

1 reference

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Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition

24 September 2018

1 reference

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Differences between study-specific and subject-specific heart rate corrections of the QT interval in investigations of drug induced QTc prolongation.

24 September 2018

1 reference

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Quantitative relationship between myocardial concentration of tacrolimus and QT prolongation in guinea pigs: pharmacokinetic/pharmacodynamic model incorporating a site of adverse effect

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1 reference

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Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview

24 September 2018

1 reference

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Inhibitory actions of the selective serotonin re-uptake inhibitor citalopram on HERG and ventricular L-type calcium currents

24 September 2018

1 reference

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Citalopram and Torsades de Pointes. A case report

24 September 2018

1 reference

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Activated charcoal reduces the need for N-acetylcysteine treatment after acetaminophen (paracetamol) overdose

24 September 2018

1 reference

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Estimating potency for the Emax-model without attaining maximal effects.

24 September 2018

1 reference

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Bayesian measures of model complexity and fit

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1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02546.X

An evaluation of the impact of gender and age on QT dispersion in healthy subjects

21 January 2018

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12 December 2020

Gastrointestinal clearance of drugs with activated charcoal

1 reference

12 December 2020

Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans

1 reference

12 December 2020

Cardiac safety of citalopram: prospective trials and retrospective analyses

1 reference

12 December 2020

10.1111/J.1365-2125.2005.02546.X

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

1884996