S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen. (Q35826926)

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scientific article published in October 2005

Language	Label	Description	Also known as
English	S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.	scientific article published in October 2005

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scholarly article

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7 January 2020

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen (English)

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7 January 2020

6-O-demethylnaproxen

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ChEBI release 2020-05-28

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Peter I Mackenzie

3

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7 January 2020

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Kushari Bowalgaha

1

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7 January 2020

David J Elliot

2

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7 January 2020

Kathleen M Knights

4

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7 January 2020

Stellan Swedmark

5

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7 January 2020

John O Miners

6

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1 October 2005

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7 January 2020

British Journal of Clinical Pharmacology

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7 January 2020

60

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7 January 2020

4

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7 January 2020

423-433

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Protein measurement with the Folin phenol reagent

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Human UDP-glucuronosyltransferases: metabolism, expression, and disease

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Nonspecific binding of drugs to human liver microsomes

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The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

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The pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl glucuronides in humans. Effect of cimetidine

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Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

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Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

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Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

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The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases

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Nonlinear plasma level response to high doses of naproxen

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12 December 2020

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Naproxen-probenecid interaction

1 reference

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12 December 2020

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Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine

1 reference

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Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

1 reference

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Preclinical prediction of factors influencing the elimination of 5,6-dimethylxanthenone-4-acetic acid, a new anticancer drug

1 reference

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Identifiers

10.1111/J.1365-2125.2005.02446.X

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7 January 2020

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Europe PubMed Central

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7 January 2020

1 reference

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7 January 2020

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