GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model (Q35808904)

10 August 2017

GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model (English)

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10 August 2017

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3

Cynthia Hawkins

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10 August 2017

Deepak Kamnasaran

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10 August 2017

Baoping Qian

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2

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10 August 2017

William L Stanford

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4

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10 August 2017

Abhijit Guha

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5

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10 August 2017

language of work or name

English

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publication date

26 April 2007

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10 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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10 August 2017

104

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10 August 2017

19

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10 August 2017

8053-8058

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High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Up-regulation of VEGF expression and related neo-angiogenesis in childhood high-grade gliomas: implications for anti-angiogenic anti-neoplastic therapy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Expression of GATA6 in the human and mouse central nervous system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Microarray analysis of temporal gene responses to ionizing radiation in two glioblastoma cell lines: up-regulation of DNA repair genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Adrenocortical tumorigenesis in transgenic mice: the role of luteinizing hormone receptor and transcription factors GATA-4 and GATA-61.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Gene-trap mutagenesis: past, present and beyond

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Expression of retinoblastoma gene product and p21 (WAF1/Cip 1) protein in gliomas: correlations with proliferation markers, p53 expression and survival

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

A tiger behind many doors: multiple genetic pathways to malignant glioma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Proliferation of human malignant astrocytomas is dependent on Ras activation.

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Gene expression profiling of gliomas strongly predicts survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Identification of molecular subtypes of glioblastoma by gene expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Isotype-specific Ras.GTP-levels predict the efficacy of farnesyl transferase inhibitors against human astrocytomas regardless of Ras mutational status.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

National survey of patterns of care for brain-tumor patients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Genetic alterations in localized prostate cancer: Identification of a common region of deletion on chromosome arm 18q

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611669104

Frequent loss of heterozygosity on chromosome 18 in ovarian adenocarcinoma which does not always include the DCC locus

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876570

Frequent loss of heterozygosity on chromosome arm 18q in squamous cell carcinomas. Identification of 2 regions of loss--18q11.1-q12.3 and 18q21.1-q23

15 November 2018

1 reference

12 December 2020

Anomalous expression of epithelial differentiation-determining GATA factors in ovarian tumorigenesis

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12 December 2020

Cyclin A downregulation and p21(cip1) upregulation correlate with GATA-6-induced growth arrest in glomerular mesangial cells

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12 December 2020

Genomic organization and characterization of the mouse ELYS gene

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0611669104

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10 August 2017

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10 August 2017

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