Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance (Q35802661)

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7 December 2019

title

Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance (English)

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7 December 2019

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4

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7 December 2019

author name string

G Schaber

1

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7 December 2019

I Stevens

2

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7 December 2019

H J Gaertner

3

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7 December 2019

U Breyer-Pfaff

5

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7 December 2019

language of work or name

English

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publication date

1 November 1998

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7 December 2019

number of pages

7

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British Journal of Clinical Pharmacology

inferred from page(s)

published in

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7 December 2019

volume

46

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7 December 2019

issue

5

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7 December 2019

page(s)

453-459

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The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

7 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Pharmacokinetics of clozapine and risperidone: a review of recent literature

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Pharmacokinetics and pharmacodynamics of clozapine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Disposition of clozapine in man: lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Validity of creatinine clearance estimates in the assessment of renal function.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Urinary metabolites of amitriptylinoxide and amitriptyline in single-dose experiments and during continuous therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

The metabolic fate of the antidepressive agent amitriptylinoxide in man

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Binding of tricyclic antidepressants and perazine to human plasma. Methodology and findings in normals

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

CSF and serum concentrations of clozapine and its demethyl metabolite: a pilot study.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

25 September 2018

The history of clozapine

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.00822.X

Determination of clozapine, norclozapine, and clozapine-N-oxide in serum by liquid chromatography

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate

23 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Clozapine and metabolites: concentrations in serum and clinical findings during treatment of chronically psychotic patients

23 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873700

Exchange of aromatically bound halogen for OH- and SCH3-groups in metabolising clozapine in the human organism (author's transl)

23 October 2018

1 reference

12 December 2020

Imipramine serum protein binding in healthy subjects

1 reference

12 December 2020

Clinical pharmacokinetics of clozapine in chronic schizophrenic patients

1 reference

12 December 2020

1 reference

12 December 2020

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues

1 reference

12 December 2020

Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detection

1 reference

12 December 2020

Identification of clozapine N(+)-glucuronide in the urine of patients treated with clozapine using electrospray mass spectrometry

1 reference

12 December 2020

Decomposition of clozapine N-oxide in the qualitative and quantitative analysis of clozapine and its metabolites

1 reference

12 December 2020

Rapid formation of clozapine in guinea-pigs and man following clozapine-N-oxide administration

1 reference

12 December 2020

Clozapine serum levels and side effects during steady state treatment of schizophrenic patients: a cross-sectional study

1 reference

12 December 2020

Clozapine treatment of schizophrenia

1 reference

12 December 2020

1 reference

12 December 2020

N-oxygenation of clozapine by flavin-containing monooxygenase

1 reference

12 December 2020

Biotransformation of clozapine in humans

1 reference

12 December 2020

Automated determination of clozapine and major metabolites in serum and urine

1 reference

12 December 2020

Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes

1 reference

12 December 2020

Pharmacokinetic interactions of clozapine with selective serotonin reuptake inhibitors: differential effects of fluvoxamine and paroxetine in a prospective study

1 reference

12 December 2020

The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepine (clozapine) in mice, dogs and human subjects

1 reference

12 December 2020

Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms

1 reference

12 December 2020

10.1046/J.1365-2125.1998.00822.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9833598%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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7 December 2019

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