Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes (Q35801843)

10 August 2017

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title

Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes (English)

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10 August 2017

Nezam H Afdhal

2

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author name string

David Q-H Wang

series ordinal

1

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10 August 2017

1 April 2004

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Current gastroenterology reports

10 August 2017

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10 August 2017

6

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10 August 2017

2

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10 August 2017

140-150

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https://scigraph.springernature.com/pub.10.1007/s11894-004-0042-1

10 August 2017

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cites work

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Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice

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Functional investigation of a gene encoding pteridine glycosyltransferase for cyanopterin synthesis in Synechocystis sp. PCC 6803.

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Apolipoprotein E polymorphism and lithogenic factors in gallbladder bile

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Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: studies in C57BL/6 apolipoprotein E knockout mice

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Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: identical pathways to corresponding model biles with three predominating sequences

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Gallstone cholesterol content is related to apolipoprotein E polymorphism.

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The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood

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Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.

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INDUCTION OF GALLSTONES IN MICE BY FEEDING A CHOLESTEROL-CHOLIC ACID CONTAINING DIET

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Impaired biliary cholesterol secretion and decreased gallstone formation in apolipoprotein E-deficient mice fed a high-cholesterol diet

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Bovine gallbladder mucin accelerates cholesterol monohydrate crystal growth in model bile

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Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse

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Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice

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Susceptibility to murine cholesterol gallstone formation is not affected by partial disruption of the HDL receptor SR-BI.

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Filamentous, helical, and tubular microstructures during cholesterol crystallization from bile. Evidence that cholesterol does not nucleate classic monohydrate plates

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Mechanisms of gallstone formation in women. Effects of exogenous estrogen (Premarin) and dietary cholesterol on hepatic lipid metabolism

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Disruption of the sterol carrier protein 2 gene in mice impairs biliary lipid and hepatic cholesterol metabolism

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Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts

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12 December 2020

Intestinal cholesterol absorption efficiency in man is related to apoprotein E phenotype

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12 December 2020

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

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High familial prevalence of gallstones in the first-degree relatives of gallstone patients.

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The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man

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Genetic dissection of complex traits

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Etiologic significance of defects in cholesterol, phospholipid, and bile acid metabolism in the liver of patients with intrahepatic calculi

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Apolipoprotein B-100 gene Xba I polymorphism and cholesterol gallstone disease

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Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease

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Tamoxifen and gallstone formation in postmenopausal breast cancer patients: retrospective cohort study

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Lith genes control mucin accumulation, cholesterol crystallization, and gallstone formation in A/J and AKR/J inbred mice

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Cholesterol crystallization in human gallbladder bile: relation to gallstone number, bile composition, and apolipoprotein E4 isoform.

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Restoration of gallstone susceptibility by leptin in C57BL/6J ob/ob mice

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Biliary lipid secretion, bile acid metabolism, and gallstone formation are not impaired in hepatic lipase-deficient mice

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Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physical-chemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydroph

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Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk

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Polymorphisms at the apoB, apoA-I, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease.

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Phenotypic characterization of lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice. Pathophysiology Of biliary lipid secretion.

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Genetics and epidemiology of gallbladder disease in New World native peoples

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Lithogenic bile in siblings of young women with cholelithiasis

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Different susceptibilities to the formation of cholesterol gallstones in mice

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Familial occurrence of gallstone disease. Incidence in parents of young patients

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12 December 2020

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

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Strain difference in mouse cholelithiasis and the effect of taurine on the gallstone formation in C57BL/C mice

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Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains

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Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: physical-chemistry of gallbladder bile.

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12 December 2020

Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice

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Cholesterol saturation, not proteins or cholecystitis, is critical for crystal formation in human gallbladder bile.

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12 December 2020

From QTL to gene: the harvest begins

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12 December 2020

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

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12 December 2020

Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism

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Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice

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12 December 2020

Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype

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12 December 2020

CCK receptor dysfunction in muscle membranes from human gallbladders with cholesterol stones

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12 December 2020

Quantitative trait loci mapping for cholesterol gallstones in AKR/J and C57L/J strains of mice.

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12 December 2020

Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile

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12 December 2020

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

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12 December 2020

Risk factors for gallstone formation during rapid loss of weight

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12 December 2020

Cholesterol crystals and the formation of cholesterol gallstones.

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12 December 2020

Nature and composition of biliary sludge

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12 December 2020

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles

1 reference

12 December 2020

MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis

1 reference

12 December 2020

Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis

1 reference

12 December 2020

Lithogenic bile among young Indian women

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12 December 2020

ABCB4 gene mutation-associated cholelithiasis in adults

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12 December 2020

An increased familial frequency of gallstones

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12 December 2020

Apolipoprotein E polymorphism and gallstones.

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12 December 2020

In vitro effects of cholecystokinin fragments on human gallbladders. Evidence for an altered CCK-receptor structure in a subgroup of patients with gallstones

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12 December 2020

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: integrated activities of hepatic lipid regulatory enzymes

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12 December 2020

No pathophysiologic relationship of soluble biliary proteins to cholesterol crystallization in human bile

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12 December 2020

Direct G protein activation reverses impaired CCK signaling in human gallbladders with cholesterol stones

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12 December 2020

Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice

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12 December 2020

Abnormal processing of the human cholecystokinin receptor gene in association with gallstones and obesity

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12 December 2020

Role of Gallbladder Mucus Hypersecretion in the Evolution of Cholesterol Gallstones

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12 December 2020

FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice

1 reference

12 December 2020

Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice

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12 December 2020

Biliary lipid composition in monozygotic and dizygotic pairs of twins

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12 December 2020

Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis

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12 December 2020

Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

1 reference

12 December 2020

10.1007/S11894-004-0042-1

Identifiers

DOI

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10 August 2017

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PubMed ID

15191694