Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction (Q35796953)

10 August 2017

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction (English)

1 reference

10 August 2017

12

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4 June 2020

Laurence H Arnold

1

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4 June 2020

David Goldstone

9

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4 June 2020

author name string

Harriet C T Groom

2

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4 June 2020

Simone Kunzelmann

3

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4 June 2020

David Schwefel

4

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4 June 2020

Sarah J Caswell

5

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4 June 2020

Paula Ordonez

6

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4 June 2020

Melanie C Mann

7

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4 June 2020

Sabrina Rueschenbaum

8

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4 June 2020

Simon Pennell

10

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4 June 2020

Steven A Howell

11

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4 June 2020

Michelle Webb

13

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4 June 2020

Ian A Taylor

14

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4 June 2020

Kate N Bishop

15

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4 June 2020

publication date

2 October 2015

1 reference

10 August 2017

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4 June 2020

volume

11

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4 June 2020

page(s)

e1005194

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4 June 2020

issue

10

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Creative Commons Attribution 4.0 International

4 June 2020

copyright license

start time

2 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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27 July 2018

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27 July 2018

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The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

27 July 2018

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GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state

27 July 2018

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27 July 2018

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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

27 July 2018

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Mechanism of allosteric activation of SAMHD1 by dGTP

27 July 2018

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Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.

27 July 2018

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Restriction of retroviral infection of macrophages

27 July 2018

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The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

27 July 2018

1 reference

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Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection

27 July 2018

1 reference

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SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons

27 July 2018

1 reference

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Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

27 July 2018

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The gammaretroviral p12 protein has multiple domains that function during the early stages of replication

27 July 2018

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Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages

27 July 2018

1 reference

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HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

27 July 2018

1 reference

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SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

27 July 2018

1 reference

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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

27 July 2018

1 reference

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

27 July 2018

1 reference

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

27 July 2018

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Features and development of Coot

27 July 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

27 July 2018

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27 July 2018

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Molecular replacement with MOLREP

27 July 2018

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27 July 2018

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A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection

27 July 2018

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27 July 2018

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Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules

27 July 2018

1 reference

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27 July 2018

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

27 July 2018

1 reference

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Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

27 July 2018

1 reference

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A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis

27 July 2018

1 reference

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SAM domains: uniform structure, diversity of function

27 July 2018

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Use of a transient assay for studying the genetic determinants of Fv1 restriction

27 July 2018

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The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

27 July 2018

1 reference

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Mechanism of inorganic phosphate interaction with phosphate binding protein from Escherichia coli.

27 July 2018

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Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes

27 July 2018

1 reference

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

27 July 2018

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Direct, real-time measurement of rapid inorganic phosphate release using a novel fluorescent probe and its application to actomyosin subfragment 1 ATPase

27 July 2018

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An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells.

27 July 2018

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The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

25 September 2018

1 reference

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Single-stranded nucleic acids promote SAMHD1 complex formation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac

25 September 2018

1 reference

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Subunit-selective mutational analysis and tissue culture evaluations of the interactions of the E138K and M184I mutations in HIV-1 reverse transcriptase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication.

25 September 2018

1 reference

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Integration, scaling, space-group assignment and post-refinement

25 September 2018

1 reference

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Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592219

A graphical user interface to the CCP4 program suite

25 September 2018

1 reference

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In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium

25 September 2018

1 reference

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Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26431200

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1005194

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26431200%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26431200%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26431200%20AND%20SRC:MED&resulttype=core&format=json