Therapeutic potential of targeting IL-1 and IL-18 in inflammation (Q35790840)

10 August 2017

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title

Therapeutic potential of targeting IL-1 and IL-18 in inflammation (English)

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10 August 2017

Martin Braddock

1

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10 August 2017

Anthony Quinn

series ordinal

2

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10 August 2017

Jan Canvin

series ordinal

3

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10 August 2017

language of work or name

English

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publication date

1 June 2004

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Expert Opinion on Biological Therapy

10 August 2017

published in

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10 August 2017

volume

4

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10 August 2017

issue

6

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10 August 2017

page(s)

847-860

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Evolution of interleukin-1beta

10 August 2017

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The saga of the discovery of IL-1 and TNF and their specific inhibitors in the pathogenesis and treatment of rheumatoid arthritis

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A proinflammatory role for IL-18 in rheumatoid arthritis

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Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation

21 January 2018

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Interleukin 1 beta in synovial fluid is related to local disease activity in rheumatoid arthritis

21 January 2018

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Systemic anti-inflammatory mediators in COPD: increase in soluble interleukin 1 receptor II during treatment of exacerbations

21 January 2018

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Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of synovial tissue

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Cytokines in symptomatic asthma airways

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Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

21 January 2018

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Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals.

21 January 2018

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Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution.

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Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation.

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Interleukin-18 levels in the plasma of psoriatic patients correlate with the extent of skin lesions and the PASI score.

21 January 2018

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Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina

21 January 2018

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Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

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Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

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Defective NK cell activity and Th1 response in IL-18-deficient mice

21 January 2018

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Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis

21 January 2018

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Molecular cloning of the interleukin-1 beta converting enzyme

21 January 2018

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

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Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha

21 January 2018

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Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli

21 January 2018

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Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

21 January 2018

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Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1beta/IL-1R(I) complex.

21 January 2018

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MyD88, an adapter protein involved in interleukin-1 signaling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The membrane form of the type II IL-1 receptor accounts for inhibitory function

21 January 2018

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IL-1 beta scavenging by the type II IL-1 decoy receptor in human neutrophils

21 January 2018

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Interleukin-1 receptor antagonist

21 January 2018

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Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Anti-interleukin-1 and anti-tumor necrosis factor-alpha synergistically inhibit adjuvant arthritis in Lewis rats

21 January 2018

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21 January 2018

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Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data

21 January 2018

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Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

21 January 2018

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Long-term efficacy and safety of etanercept in children with polyarticular-course juvenile rheumatoid arthritis: interim results from an ongoing multicenter, open-label, extended-treatment trial

21 January 2018

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Cytokine traps: multi-component, high-affinity blockers of cytokine action

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14712598.4.6.847

1 reference

10 August 2017

1 reference