Is there enough gp120 in the body fluids of HIV-1-infected individuals to have biologically significant effects? (Q35785806)

10 August 2017

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title

Is there enough gp120 in the body fluids of HIV-1-infected individuals to have biologically significant effects? (English)

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10 August 2017

1

P J Klasse

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10 August 2017

2

John P Moore

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PubMed ID

15165814

10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

323

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10 August 2017

1

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10 August 2017

1-8

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The role of the CD4 receptor versus HIV coreceptors in envelope-mediated apoptosis in peripheral blood mononuclear cells

10 August 2017

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Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis

7 January 2021

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Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes

7 January 2021

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Inhibition of soluble CD4 therapy by antibodies to HIV.

7 January 2021

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Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation

7 January 2021

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Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

7 January 2021

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Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus

7 January 2021

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Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5.

7 January 2021

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Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1.

7 January 2021

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Microglia in human immunodeficiency virus-associated neurodegeneration.

7 January 2021

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Long-term safety analysis of preventive HIV-1 vaccines evaluated in AIDS vaccine evaluation group NIAID-sponsored Phase I and II clinical trials.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Intra-blood-brain barrier synthesis of human immunodeficiency virus antigen and antibody in humans and chimpanzees

7 January 2021

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Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

7 January 2021

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CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

7 January 2021

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Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

7 January 2021

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Apoptotic effects in primary human umbilical vein endothelial cell cultures caused by exposure to virion-associated and cell membrane-associated HIV-1 gp120

7 January 2021

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Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4

7 January 2021

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In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells

7 January 2021

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HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

7 January 2021

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Analysis of human lung endothelial cells for susceptibility to HIV type 1 infection, coreceptor expression, and cytotoxicity of gp120 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

7 January 2021

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

7 January 2021

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Schwann cell chemokine receptors mediate HIV-1 gp120 toxicity to sensory neurons

7 January 2021

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Occupancy and mechanism in antibody-mediated neutralization of animal viruses

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Lymphocyte activation by HIV-1 envelope glycoprotein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus

7 January 2021

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Human immunodeficiency virus type 1 p24 concentration measured by boosted ELISA of heat-denatured plasma correlates with decline in CD4 cells, progression to AIDS, and survival: comparison with viral RNA measurement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Simple methods for monitoring HIV-1 and HIV-2 gp120 binding to soluble CD4 by enzyme-linked immunosorbent assay: HIV-2 has a 25-fold lower affinity than HIV-1 for soluble CD4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Sensitive ELISA for the gp120 and gp160 surface glycoproteins of HIV-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Hepatitis C and Human Immunodeficiency Virus Envelope Proteins Cooperatively Induce Hepatocytic Apoptosis via an Innocent Bystander Mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

HIV-1 antibody--debris or virion?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

HIV-1 gp120 receptor on CD4-negative brain cells activates a tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Quantitative and sensitive detection of immune-complexed and free HIV antigen after boiling of serum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Impairment of T Cell Receptor-Dependent Stimulation in CD4+ Lymphocytes after Contact with Membrane-Bound HIV-1 Envelope Glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Diversity of receptors binding HIV on dendritic cell subsets

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

HIV-1 attachment: another look.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Human Immunodeficiency Virus–Induced Apoptosis of Human Hepatocytes via CXCR4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

HIV envelope proteins differentially utilize CXCR4 and CCR5 coreceptors for induction of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

Identification of CXCR4 domains that support coreceptor and chemokine receptor functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

7 January 2021

Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

7 January 2021

Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

7 January 2021

Binding kinetics of ecotropic (Moloney) murine leukemia retrovirus with NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.03.003

7 January 2021

10.1016/J.VIROL.2004.03.003

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15165814