Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications (Q35784542)

10 August 2017

title

Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications (English)

1 reference

10 August 2017

1 reference

Arturo Becerra

2

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Antonio Lazcano

object named as

Antonio Lazcano

series ordinal

4

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author name string

Rodrigo Jácome

series ordinal

1

1 reference

10 August 2017

Samuel Ponce de León

series ordinal

3

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10 August 2017

language of work or name

English

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publication date

23 September 2015

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10 August 2017

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10 August 2017

volume

10

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10 August 2017

issue

9

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10 August 2017

page(s)

e0139001

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Creative Commons Attribution 4.0 International

10 August 2017

copyright license

start time

23 September 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity

12 July 2018

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A cutting-edge view on the current state of antiviral drug development

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12 July 2018

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12 July 2018

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Favipiravir (T-705) inhibits in vitro norovirus replication

12 July 2018

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Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations.

12 July 2018

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First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses

12 July 2018

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12 July 2018

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Negative-strand RNA viruses: the plant-infecting counterparts

12 July 2018

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Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

12 July 2018

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12 July 2018

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12 July 2018

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Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription

12 July 2018

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12 July 2018

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Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

12 July 2018

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Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models

12 July 2018

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12 July 2018

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Effect of T-705 treatment on western equine encephalitis in a mouse model

12 July 2018

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The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

12 July 2018

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Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition

12 July 2018

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Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Sequential structures provide insights into the fidelity of RNA replication

12 July 2018

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Structure and function of RNA replication

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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DNA polymerases: structural diversity and common mechanisms

12 July 2018

1 reference

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Characterization of the L gene and 5' trailer region of Ebola virus

12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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12 July 2018

1 reference

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Polymerase activity of in vitro mutated rabies virus L protein

12 July 2018

1 reference

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12 July 2018

1 reference

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

12 July 2018

1 reference

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E. coli DNA polymerase I as a reverse transcriptase

12 July 2018

1 reference

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1 reference

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Function and structure relationships in DNA polymerases

12 July 2018

1 reference

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12 July 2018

1 reference

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Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread

12 July 2018

1 reference

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Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses

12 July 2018

1 reference

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Expression of animal virus genomes

12 July 2018

1 reference

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On the early evolution of RNA polymerase

12 July 2018

1 reference

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Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug

12 July 2018

1 reference

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Origins and evolutionary relationships of retroviruses

12 July 2018

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3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

12 July 2018

1 reference

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Sequence comparison of five polymerases (L proteins) of unsegmented negative-strand RNA viruses: theoretical assignment of functional domains

12 July 2018

1 reference

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The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

On the early emergence of reverse transcription: theoretical basis and experimental evidence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Ebola haemorrhagic fever in Zaire, 1976

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Mechanism of RNA synthesis initiation by the vesicular stomatitis virus polymerase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Nucleic acid polymerases use a general acid for nucleotidyl transfer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Effect of single amino acid mutations in the conserved GDNQ motif of L protein of Rinderpest virus on RNA synthesis in vitro and in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

Analysis of the mutations in the active site of the RNA-dependent RNA polymerase of human parainfluenza virus type 3 (HPIV3).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634563

10.1371/JOURNAL.PONE.0139001

25 September 2018

Identifiers

DOI

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference