The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas. (Q35769579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25650326%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas (English)

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29 February 2020

0 references

1

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29 February 2020

author name string

Carey L Watson

2

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29 February 2020

Cameron Ingram

3

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29 February 2020

Michael A Helmrath

4

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29 February 2020

James M Wells

5

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29 February 2020

language of work or name

English

0 references

publication date

3 February 2015

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29 February 2020

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29 February 2020

volume

64

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29 February 2020

issue

7

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29 February 2020

page(s)

2497-2505

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Genome engineering using the CRISPR-Cas9 system

29 February 2020

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12 July 2018

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12 July 2018

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Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3.

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Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development

12 July 2018

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Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

12 July 2018

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Pancreatic neurogenin 3-expressing cells are unipotent islet precursors

12 July 2018

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12 July 2018

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Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation

12 July 2018

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Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

12 July 2018

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

12 July 2018

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Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate.

12 July 2018

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Regulation of neurogenin stability by ubiquitin-mediated proteolysis.

12 July 2018

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IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

12 July 2018

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12 July 2018

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NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas

12 July 2018

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Opposing actions of Arx and Pax4 in endocrine pancreas development

12 July 2018

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Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

12 July 2018

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Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

12 July 2018

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

12 July 2018

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12 July 2018

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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas

12 July 2018

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Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

12 July 2018

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

12 July 2018

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12 July 2018

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12 July 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Mutant neurogenin-3 in congenital malabsorptive diarrhea

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25650326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25650326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25650326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB14-1412

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25650326%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25650326%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference