An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection (Q35751670)

10 August 2017

An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection (English)

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10 August 2017

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5

Mahendra S Rao

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10 August 2017

Xianmin Zeng

1

1 reference

10 August 2017

Jia Chen

2

1 reference

10 August 2017

Xiaolin Deng

3

1 reference

10 August 2017

Ying Liu

4

1 reference

10 August 2017

Jean-Lud Cadet

6

1 reference

10 August 2017

William J Freed

7

1 reference

10 August 2017

language of work or name

English

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publication date

1 December 2006

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10 August 2017

Neuropsychopharmacology

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10 August 2017

31

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10 August 2017

12

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10 August 2017

2708-2715

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1301125

10 August 2017

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cites work

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Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

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Collection of neural inducing factors from PA6 cells using heparin solution and their immobilization on plastic culture dishes for the induction of neurons from embryonic stem cells.

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2 October 2017

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Dopaminergic differentiation of human embryonic stem cells

2 October 2017

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Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF.

2 October 2017

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Derivation of midbrain dopamine neurons from human embryonic stem cells

2 October 2017

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2 October 2017

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GDNF promotes neuronal differentiation and dopaminergic development of mouse mesencephalic neurospheres

2 October 2017

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Stable Expression of hrGFP by Mouse Embryonic Stem Cells: Promoter Activity in the Undifferentiated State and During Dopaminergic Neural Differentiation

2 October 2017

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Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: a potential, new model of Parkinson's disease

2 October 2017

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The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?

2 October 2017

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Pathogenic role of glial cells in Parkinson's disease.

2 October 2017

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Environmental factors in Parkinson's disease

2 October 2017

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Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease.

2 October 2017

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Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats

2 October 2017

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The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

2 October 2017

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

2 October 2017

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Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons.

2 October 2017

1 reference

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Ceramide prevents motoneuronal cell death through inhibition of oxidative signal

2 October 2017

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Parkinson disease in twins: an etiologic study

2 October 2017

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Attenuation of cochlear damage from noise trauma by an iron chelator, a free radical scavenger and glial cell line-derived neurotrophic factor in vivo

2 October 2017

1 reference

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Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos.

2 October 2017

1 reference

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Embryonic stem cell lines derived from human blastocysts

2 October 2017

1 reference

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Effects of glial cell line-derived neurotrophic factor on the nigrostriatal dopamine system in rodents and nonhuman primates.

2 October 2017

1 reference

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Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys

2 October 2017

1 reference

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GDNF improves survival and reduces apoptosis in human embryonic dopaminergic neurons in vitro

2 October 2017

1 reference

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

2 October 2017

1 reference

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Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

2 October 2017

1 reference

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

2 October 2017

1 reference

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

2 October 2017

1 reference

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Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture

2 October 2017

1 reference

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Local cerebral metabolic effects of L-dopa therapy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys

2 October 2017

1 reference

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Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity

2 October 2017

1 reference

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Strain differences in systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier

2 October 2017

1 reference

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

2 October 2017

1 reference

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Chronic parkinsonism secondary to intravenous injection of meperidine analogues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-alpha, interleukin-1beta, and nitric oxide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Free radicals and the pathobiology of brain dopamine systems

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Nucleoside transporter of cerebral microvessels and choroid plexus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Blood-brain barrier monoamine oxidase: enzyme characterization in cerebral microvessels and other tissues from six mammalian species, including human.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Evidence for neuromelanin involvement in MPTP-induced neurotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

The transcription factor Nurr1 in human NT2 cells and hNT neurons

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

N-methylated beta-carbolines protect PC12 cells from cytotoxic effect of MPP+ by attenuation of mitochondrial membrane permeability change

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Tyrosine-533 of rat dopamine transporter: involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852423

Extensive sequence divergence between the human and rat brain vesicular monoamine transporter: Possible molecular basis for species differences in the susceptibility to MPP+

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17109014

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.NPP.1301125

1 reference

10 August 2017

1 reference

10 August 2017

1 reference