NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy (Q35747174)

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scientific article published on 30 September 2011

Language	Label	Description	Also known as
English	NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy	scientific article published on 30 September 2011

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy (English)

1 reference

Europe PubMed Central

10 August 2017

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1 reference

based on heuristic

inferred from title

neurodegeneration

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based on heuristic

inferred from title

author name string

Yousuf O Ali

1

1 reference

Europe PubMed Central

10 August 2017

Kai Ruan

2

1 reference

Europe PubMed Central

10 August 2017

R Grace Zhai

3

1 reference

Europe PubMed Central

10 August 2017

publication date

30 September 2011

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Europe PubMed Central

10 August 2017

Human Molecular Genetics

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Europe PubMed Central

10 August 2017

21

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Europe PubMed Central

10 August 2017

2

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Europe PubMed Central

10 August 2017

237-250

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Europe PubMed Central

10 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3276290/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway

1 reference

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12 July 2018

Assaying locomotor, learning, and memory deficits in Drosophila models of neurodegeneration

1 reference

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Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration.

1 reference

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Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease

1 reference

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12 July 2018

The cleaved-Caspase-3 antibody is a marker of Caspase-9-like DRONC activity in Drosophila

1 reference

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Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme

1 reference

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Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model

1 reference

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Association of GSK3B with Alzheimer disease and frontotemporal dementia

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

1 reference

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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

1 reference

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1 reference

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BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION

1 reference

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1 reference

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Tau phosphorylation: physiological and pathological consequences

1 reference

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Tau pathology in Alzheimer disease and other tauopathies

1 reference

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Tau protein as a differential biomarker of tauopathies

1 reference

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U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

1 reference

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Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system

1 reference

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1 reference

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

1 reference

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Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

1 reference

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CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

1 reference

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Colocalization of Tau and Alpha-Synuclein Epitopes in Lewy Bodies

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

1 reference

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Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

1 reference

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1 reference

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The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila.

1 reference

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The in vitro formation of recombinant tau polymers: effect of phosphorylation and glycation.

1 reference

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MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

1 reference

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Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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Molecular chaperones in cellular protein folding

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Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system.

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The structural brain mutant Vacuolar medulla of Drosophila melanogaster with specific behavioral defects and cell degeneration in the adult.

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Brain levels of microtubule-associated protein tau are elevated in Alzheimer's disease: a radioimmuno-slot-blot assay for nanograms of the protein.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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Microtubule-associated protein tau is a substrate of ATP/Mg(2+)-dependent proteasome protease system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

25 September 2018

Proteasomal degradation of tau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276290

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1 reference

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Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

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1 reference

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1 reference

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25 September 2018

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1 reference

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1 reference

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1 reference

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1 reference

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Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β

1 reference

https://pubmed.ncbi.nlm.nih.gov/21965302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

1 reference

https://pubmed.ncbi.nlm.nih.gov/21965302

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDR449

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Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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