Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1. (Q35743984)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21693693%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1 (English)

1 reference

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5 February 2020

3

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5 February 2020

author name string

Leah Wuescher

1

1 reference

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5 February 2020

Kristine Angevine

2

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5 February 2020

Sadeesh Ramakrishnan

4

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5 February 2020

Sonia M Najjar

5

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5 February 2020

Edith J Mensah-Osman

6

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5 February 2020

publication date

21 June 2011

1 reference

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American Journal of Physiology - Endocrinology and Metabolism

5 February 2020

published in

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5 February 2020

volume

301

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5 February 2020

issue

3

1 reference

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5 February 2020

page(s)

E474-83

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The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.

5 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Insulin acutely decreases hepatic fatty acid synthase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Menin molecular interactions: insights into normal functions and tumorigenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Regulation of insulin action by CEACAM1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Insulin stimulates pp120 endocytosis in cells co-expressing insulin receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Multiple endocrine neoplasia type 1 (MEN 1) is associated with an increased prevalence of diabetes mellitus and impaired fasting glucose.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3275149

Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21693693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical studies of multiple endocrine neoplasia type 1 (MEN1)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21693693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPENDO.00022.2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21693693%20AND%20SRC:MED&resulttype=core&format=json

release_7foviuv34nfdtklcmeau47zzoe

5 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7foviuv34nfdtklcmeau47zzoe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21693693%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference