A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck. (Q35743883)

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24 January 2020

title

A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck (English)

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24 January 2020

main subject

squamous cell carcinoma

1 reference

4

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24 January 2020

Ezra E Cohen

17

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16

Everett E Vokes

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5

Tanguy Y Seiwert

1 reference

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12

Kerstin M Stenson

1 reference

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24 January 2020

10

Mark W Lingen

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author name string

Jonas A de Souza

1

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24 January 2020

Darren W Davis

2

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24 January 2020

Yujian Zhang

3

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24 January 2020

Serdal Aktolga

6

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24 January 2020

Stuart J Wong

7

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24 January 2020

Mark F Kozloff

8

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Sreenivasa Nattam

9

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Rangesh Kunnavakkam

11

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Elizabeth A Blair

13

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Jeffrey Bozeman

14

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Janet E Dancey

15

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language of work or name

English

0 references

publication date

27 February 2012

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24 January 2020

published in

Clinical Cancer Research

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24 January 2020

volume

18

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issue

8

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page(s)

2336-2343

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Effects of lapatinib monotherapy: results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck

24 January 2020

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1 reference

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The mutational landscape of head and neck squamous cell carcinoma

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A phase I and pharmacokinetic study of oral lapatinib administered once or twice daily in patients with solid malignancies

12 July 2018

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Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell lines

12 July 2018

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12 July 2018

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Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck

12 July 2018

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Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas

12 July 2018

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Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group

12 July 2018

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Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668.

12 July 2018

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Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies

12 July 2018

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Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck

12 July 2018

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Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 December 2020

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12 December 2020

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12 December 2020

A retrospective analysis of the outcome of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck refractory to a platinum-based chemotherapy

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12 December 2020

10.1158/1078-0432.CCR-11-2825

Identifiers

DOI

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24 January 2020

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24 January 2020

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