Challenges for the development of ribonucleoside analogues as inducers of error catastrophe (Q35742174)

10 August 2017

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title

Challenges for the development of ribonucleoside analogues as inducers of error catastrophe (English)

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10 August 2017

2

Craig E Cameron

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10 August 2017

Jason D Graci

1

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10 August 2017

1 January 2004

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Antiviral Chemistry & Chemotherapy

10 August 2017

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10 August 2017

15

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10 August 2017

1-13

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10 August 2017

1

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Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

10 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular approaches for the treatment of hemorrhagic fever virus infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

RNA editing by adenosine deaminases that act on RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Role of membrane trafficking in plasma membrane solute transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular biology and regulation of nucleoside and nucleobase transporter proteins in eukaryotes and prokaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Biased (A-->I) hypermutation of animal RNA virus genomes

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020401500101

Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

RNA virus error catastrophe: direct molecular test by using ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Interferon and ribavirin vs interferon alone in the re-treatment of chronic hepatitis C previously nonresponsive to interferon: A meta-analysis of randomized trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Mutation rates among RNA viruses

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020401500101

Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020401500101

Nucleoside and nucleobase transport systems of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

DNA deamination mediates innate immunity to retroviral infection

21 January 2018

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https://api.crossref.org/works/10.1177%2F095632020401500101

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Embryotoxic, teratogenic, and metabolic effects of ribavirin in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Respiratory Syncytial Virus: Update on Infection, Treatment, and Prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Survey and summary: The applications of universal DNA base analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The relationship between the metabolism of ribavirin and its proposed mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Synthesis and RNA polymerase incorporation of the degenerate ribonucleotide analogue rPTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The mechanism of mutation induction by a hydrogen bond ambivalent, bicyclic N4-oxy-2'-deoxycytidine in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

A universal nucleoside for use at ambiguous sites in DNA primers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The metabolism of ribavirin in erythrocytes and nucleated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Efficient Virus Extinction by Combinations of a Mutagen and Antiviral Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosi

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Control of messenger RNA stability in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Mutations that confer resistance to mycophenolic acid and ribavirin on sindbis virus map to the nonstructural protein nsP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Ribavirin causes error catastrophe during Hantaan virus replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The structure of inosine 5'-monophosphate dehydrogenase and the design of novel inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The ribavirin analog ICN 17261 demonstrates reduced toxicity and antiviral effects with retention of both immunomodulatory activity and reduction of hepatitis-induced serum alanine aminotransferase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Physiological concentrations of purines and pyrimidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Specific interference with gene function by double-stranded RNA in early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Elevated activity of the large form of ADAR1 in vivo: Very efficient RNA editing occurs in the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

Metabolism of 5-amino-1-β-d-ribofuranosyl- imidazole-4-carboxamide and related five-membered heterocycles to 5′-triphosphates in human blood and L5178Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020401500101

10.1177/095632020401500101

21 January 2018

Identifiers

DOI

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10 August 2017

1 reference

PubMed ID

15074710