LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway. (Q35740934)

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17 February 2020

title

LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway (English)

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17 February 2020

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Ji-An Yang

1

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17 February 2020

Bao-Hui Liu

2

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17 February 2020

Ling-Min Shao

3

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17 February 2020

Zhen-Tao Guo

4

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17 February 2020

Qian Yang

5

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17 February 2020

Li-Quan Wu

6

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17 February 2020

Bao-Wei Ji

7

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17 February 2020

Xiao-Nan Zhu

8

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17 February 2020

Shen-Qi Zhang

9

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17 February 2020

Cheng-Jun Li

10

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17 February 2020

Qian-Xue Chen

11

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17 February 2020

publication date

1 April 2015

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International Journal of Clinical and Experimental Pathology

17 February 2020

published in

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17 February 2020

volume

8

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17 February 2020

issue

4

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17 February 2020

page(s)

3580-3590

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Repair mechanisms help glioblastoma resist treatment

17 February 2020

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The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

27 July 2018

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LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.

27 July 2018

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LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling

27 July 2018

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27 July 2018

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Analysis of hydrophilic and lipophilic choline compounds in radioresistant and radiosensitive glioblastoma cell lines by HILIC-ESI-MS/MS.

27 July 2018

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Differential gene expression profiles of radioresistant non-small-cell lung cancer cell lines established by fractionated irradiation: tumor protein p53-inducible protein 3 confers sensitivity to ionizing radiation

27 July 2018

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Mechanisms of double-strand break repair in somatic mammalian cells

27 July 2018

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Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells

27 July 2018

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Cytotoxicity and radiosensitization effect of TRA-8 on radioresistant human larynx squamous carcinoma cells.

27 July 2018

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Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

27 July 2018

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PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

27 July 2018

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27 July 2018

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27 July 2018

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Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

27 July 2018

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Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

27 July 2018

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27 July 2018

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LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2.

27 July 2018

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LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling.

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

Identifiers

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17 February 2020

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