Biology of gastrointestinal stromal tumors: KIT mutations and beyond (Q35740268)

10 August 2017

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title

Biology of gastrointestinal stromal tumors: KIT mutations and beyond (English)

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Christopher D. M. Fletcher

10 August 2017

series ordinal

3

object named as

Christopher D Fletcher

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10 August 2017

Anette Duensing

1

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PubMed ID

15069768

10 August 2017

Michael C Heinrich

series ordinal

2

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PubMed ID

15069768

10 August 2017

Jonathan A Fletcher

series ordinal

4

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10 August 2017

1 January 2004

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10 August 2017

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10 August 2017

22

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10 August 2017

106-116

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10 August 2017

1

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Gastrointestinal stromal tumors and leiomyosarcoma of the abdomen and retroperitoneum: a clinical comparison.

10 August 2017

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Prognosis of gastrointestinal smooth-muscle (stromal) tumors: dependence on anatomic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Developmental origin and Kit-dependent development of the interstitial cells of cajal in the mammalian small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Disturbed intestinal movement, bile reflux to the stomach, and deficiency of c-kit-expressing cells in Ws/Ws mutant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Disturbed pyloric motility in Ws/Ws mutant rats due to deficiency of c-kit-expressing interstitial cells of Cajal

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

c-kit protein, a transmembrane kinase: identification in tissues and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Early signaling pathways activated by c-Kit in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

The biology of stem cell factor and its receptor C-kit

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Clustering of activating mutations in c-KIT's juxtamembrane coding region in canine mast cell neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Familial gastrointestinal stromal tumours with germline mutation of the KIT gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Germline-activating mutation in the kinase domain of KIT gene in familial gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Activating c-kit gene mutations in human germ cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Three possible cytogenetic subgroups of leiomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

21 January 2018

Kit signal transduction

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https://api.crossref.org/works/10.1081%2FCNV-120027585

Stat1 associates with c-kit and is activated in response to stem cell factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Phosphatidylinositol 3 kinase contributes to the transformation of hematopoietic cells by the D816V c-Kit mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

The oncogenic TEL/PDGFR beta fusion protein induces cell death through JNK/SAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

PDGFRA activating mutations in gastrointestinal stromal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FCNV-120027585

21 January 2018

Identifiers

DOI

10.1081/CNV-120027585

1 reference

10 August 2017

1 reference

PubMed ID

15069768