Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis (Q35737634)

10 August 2017

Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis (English)

1 reference

10 August 2017

1 reference

protein ubiquitination

1 reference

Muhammad Alhawagri

1

1 reference

10 August 2017

Yasuhiro Yamanaka

2

1 reference

10 August 2017

Dean Ballard

3

1 reference

10 August 2017

Eugene Oltz

4

1 reference

10 August 2017

Yousef Abu-Amer

5

1 reference

10 August 2017

language of work or name

1 reference

12 September 2011

1 reference

Journal of Orthopaedic Research

10 August 2017

1 reference

10 August 2017

30

1 reference

10 August 2017

4

1 reference

10 August 2017

554-560

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Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

The zinc finger domain of IKKγ (NEMO) protein in health and disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

NF-kappaB modulators in osteolytic bone diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

The zinc finger of NEMO is a functional ubiquitin-binding domain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Shared principles in NF-kappaB signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Map kinase c-JUN N-terminal kinase mediates PMMA induction of osteoclasts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Osteoclasts; culprits in inflammatory osteolysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

TNF-alpha and pathologic bone resorption

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Advances in osteoclast differentiation and function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

NF-kappaB: linking inflammation and immunity to cancer development and progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Ubiquitin signalling in the NF-kappaB pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Bone implant interface, osteolysis and potential therapies.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Inflammatory diseases: is ubiquitinated NEMO at the hub?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

RANK, RANKL and OPG in inflammatory arthritis and periprosthetic osteolysis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

27 July 2018

Signaling to NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

RANKL is an essential cytokine mediator of polymethylmethacrylate particle-induced osteoclastogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

The phosphatidylinositol 3-kinase, p38, and extracellular signal-regulated kinase pathways are involved in osteoclast differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Minireview: the OPG/RANKL/RANK system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272311

Aseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies

27 July 2018

1 reference

Mechanisms modulating inflammatory osteolysis: a review with insights into therapeutic targets

21 January 2018

1 reference

Mitogen‐activated protein (MAP) kinases mediate PMMA‐induction of osteoclasts

21 January 2018

1 reference

The IKK NF-kappa B system: a treasure trove for drug development

21 January 2018

1 reference

NF-kB signaling blockade abolishes implant particle-induced osteoclastogenesis

21 January 2018

1 reference

Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis

21 January 2018

1 reference

Lymphocyte responses in patients with total hip arthroplasty

21 January 2018

1 reference

Arthroplasty membrane-derived fibroblasts directly induce osteoclast formation and osteolysis in aseptic loosening

21 January 2018

1 reference

12 December 2020

Inhibition of IKK activation, through sequestering NEMO, blocks PMMA-induced osteoclastogenesis and calvarial inflammatory osteolysis

1 reference

12 December 2020

Implant wear induces inflammation, but not osteoclastic bone resorption, in RANK(-/-) mice

1 reference

12 December 2020

Cytokine receptor profile of arthroplasty macrophages, foreign body giant cells and mature osteoclasts

1 reference

12 December 2020

The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1002/JOR.21555

1 reference

10 August 2017

1 reference

10 August 2017

1 reference