Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE. (Q35696751)

9 August 2017

Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE. (English)

1 reference

9 August 2017

1 reference

Lynn M Bekris

1

1 reference

PubMed ID

22089642

9 August 2017

Franziska Lutz

series ordinal

2

1 reference

PubMed ID

22089642

9 August 2017

Chang-En Yu

series ordinal

3

1 reference

9 August 2017

17 November 2011

1 reference

Journal of Human Genetics

9 August 2017

1 reference

9 August 2017

57

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9 August 2017

18-25

1 reference

9 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/jhg.2011.123

9 August 2017

0 references

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12 July 2018

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12 July 2018

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12 July 2018

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APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure

12 July 2018

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Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

12 July 2018

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Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.

12 July 2018

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Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association

12 July 2018

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Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

12 July 2018

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Neuronal specific regulatory elements in apolipoprotein E gene proximal promoter.

12 July 2018

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12 July 2018

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Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

12 July 2018

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Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue

12 July 2018

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Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene

12 July 2018

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Identification and characterization of transcriptional regulatory regions associated with expression of the human apolipoprotein E gene.

12 July 2018

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12 July 2018

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A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.

25 September 2018

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APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study.

25 September 2018

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Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics.

25 September 2018

1 reference

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Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain.

25 September 2018

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The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism.

25 September 2018

1 reference

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A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

25 September 2018

1 reference

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Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease.

25 September 2018

1 reference

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Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

25 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FJHG.2011.123

Apolipoprotein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22089642

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/JHG.2011.123

1 reference

9 August 2017

1 reference

9 August 2017

1 reference

PubMed ID

22089642