Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model (Q35691018)

9 August 2017

title

Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model (English)

1 reference

9 August 2017

1 reference

Kris Schauwaers

1

1 reference

9 August 2017

Karel De Gendt

2

1 reference

9 August 2017

Philippa T K Saunders

3

1 reference

9 August 2017

Nina Atanassova

4

1 reference

9 August 2017

Annemie Haelens

5

1 reference

9 August 2017

Leen Callewaert

6

1 reference

9 August 2017

Udo Moehren

7

1 reference

9 August 2017

Johannes V Swinnen

8

1 reference

9 August 2017

Guido Verhoeven

9

1 reference

9 August 2017

Guy Verrijdt

10

1 reference

9 August 2017

Frank Claessens

11

1 reference

9 August 2017

language of work or name

English

0 references

publication date

12 March 2007

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

1 reference

9 August 2017

volume

104

1 reference

9 August 2017

issue

12

1 reference

9 August 2017

page(s)

4961-4966

1 reference

Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

The sertoli cell--a hormonal target and 'super' nurse for germ cells that determines testicular size

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

The role of DNA response elements as allosteric modulators of steroid receptor function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

MatInspector and beyond: promoter analysis based on transcription factor binding sites

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Reversible immunocontraception in male monkeys immunized with eppin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

A bioinformatics-based functional analysis shows that the specifically androgen-regulated gene SARG contains an active direct repeat androgen response element in the first intron

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Selective DNA recognition by the androgen receptor as a mechanism for hormone-specific regulation of gene expression.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Dual function of an amino-terminal amphipatic helix in androgen receptor-mediated transactivation through specific and nonspecific response elements

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Localization of androgen and estrogen receptors in adult male mouse reproductive tract

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

DNA recognition by the androgen receptor: evidence for an alternative DNA-dependent dimerization, and an active role of sequences flanking the response element on transactivation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Selective DNA binding by the androgen receptor as a mechanism for hormone-specific gene regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: evidence for stimulatory effects of low estrogen levels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Normal reproductive and macrophage function in Pem homeobox gene-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Multiple receptor domains interact to permit, or restrict, androgen-specific gene activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume in the testis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

The nuclear receptor superfamily: the second decade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Molecular mechanisms of action of steroid/thyroid receptor superfamily members

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Structural determinants of DNA-binding specificity by steroid receptors.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829247

Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Structural basis of androgen receptor binding to selective androgen response elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

New androgen response elements in the murine pem promoter mediate selective transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Change of specificity mutations in androgen-selective enhancers. Evidence for a role of differential DNA binding by the androgen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Allosteric effects of DNA on transcriptional regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Rhox: a new homeobox gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Pem homeobox gene regulatory sequences that direct androgen-dependent developmentally regulated gene expression in different subregions of the epididymis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610814104

Differences in DNA binding characteristics of the androgen and glucocorticoid receptors can determine hormone-specific responses

21 January 2018

1 reference

12 December 2020

Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood

1 reference

12 December 2020

Expression of the pem homeobox gene in Sertoli cells increases the frequency of adjacent germ cells with deoxyribonucleic acid strand breaks

1 reference

12 December 2020

Implications of a polyglutamine tract in the function of the human androgen receptor

1 reference

12 December 2020

Antibodies against synthetic peptides recognize the human and rat androgen receptor

1 reference

12 December 2020

The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors

1 reference

12 December 2020

Specific androgen receptor activation by an artificial coactivator

1 reference

12 December 2020

Androgen specificity of a response unit upstream of the human secretory component gene is mediated by differential receptor binding to an essential androgen response element

1 reference

12 December 2020

The Role of Androgens in Sertoli Cell Proliferation and Functional Maturation: Studies in Mice with Total or Sertoli Cell-Selective Ablation of the Androgen Receptor

1 reference

12 December 2020

The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal Mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0610814104

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference