SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors (Q35680284)

9 August 2017

title

SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors (English)

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9 August 2017

7

Andreas Bechthold

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9 August 2017

Liliya Horbal

1

1 reference

9 August 2017

Yuriy Rebets

2

1 reference

9 August 2017

Mariya Rabyk

3

1 reference

9 August 2017

Roman Makitrynskyy

4

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9 August 2017

Andriy Luzhetskyy

5

1 reference

9 August 2017

Victor Fedorenko

6

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9 August 2017

publication date

3 January 2012

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9 August 2017

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9 August 2017

volume

2

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9 August 2017

issue

1

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9 August 2017

page(s)

1

1 reference

https://scigraph.springernature.com/pub.10.1186/2191-0855-2-1

9 August 2017

exact match

0 references

cites work

Beta-glucuronidase as a sensitive and versatile reporter in actinomycetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Crystallization and preliminary X-ray analysis of the TetR-like efflux pump regulator SimR.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

In vivo and in vitro patterns of the activity of simocyclinone D8, an angucyclinone antibiotic from Streptomyces antibioticus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Initiation of actinorhodin export in Streptomyces coelicolor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Mining and polishing of the treasure trove in the bacterial genus streptomyces

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Switched or not?: the structure of unphosphorylated CheY bound to the N terminus of FliM.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

The two-component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Characterization of the pathway-specific positive transcriptional regulator for actinorhodin biosynthesis in Streptomyces coelicolor A3(2) as a DNA-binding protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Antibiotic resistance gene cassettes derived from the omega interposon for use in E. coli and Streptomyces

12 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Coupling of the biosynthesis and export of the DNA gyrase inhibitor simocyclinone in Streptomyces antibioticus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Mapping the DNA-binding domain and target sequences of the Streptomyces peucetius daunorubicin biosynthesis regulatory protein, DnrI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Use of the native flp gene to generate in-frame unmarked mutations in Streptomyces spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2191-0855-2-1

Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Chapter 6. Regulation of antibiotic production by bacterial hormones

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Chapter 4. Analyzing the regulation of antibiotic production in streptomycetes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Phosphorylation-independent activation of the atypical response regulator NblR.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

IncP plasmids are most effective in mediating conjugation between Escherichia coli and streptomycetes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Genetic manipulation of pathway regulation for overproduction of angucycline-like antibiotic auricin in Streptomyces aureofaciens CCM 3239

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Function of lanI in regulation of landomycin A biosynthesis in Streptomyces cyanogenus S136 and cross-complementation studies with Streptomyces antibiotic regulatory proteins encoding genes

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261101

Chapter 5 Applying the Genetics of Secondary Metabolism in Model Actinomycetes to the Discovery of New Antibiotics

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22214346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simocyclinones: diversity of metabolites is dependent on fermentation conditions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22214346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/2191-0855-2-1

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

1 reference