Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule (Q35676297)

9 August 2017

Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule (English)

1 reference

9 August 2017

Chan Shan

1

1 reference

9 August 2017

Jing Lin

2

1 reference

9 August 2017

Jin-Qiang Hou

3

1 reference

9 August 2017

Hui-Yun Liu

4

1 reference

9 August 2017

Shuo-Bin Chen

5

1 reference

9 August 2017

Ai-Chun Chen

6

1 reference

9 August 2017

Tian-Miao Ou

7

1 reference

9 August 2017

Jia-Heng Tan

8

1 reference

9 August 2017

Ding Li

9

1 reference

9 August 2017

Lian-Quan Gu

10

1 reference

9 August 2017

Zhi-Shu Huang

11

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9 August 2017

language of work or name

English

0 references

publication date

27 June 2015

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9 August 2017

Nucleic Acids Research

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9 August 2017

43

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9 August 2017

14

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9 August 2017

6677-6691

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

9 August 2017

start time

8 May 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein

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Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

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Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma

27 July 2018

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

27 July 2018

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Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene

27 July 2018

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Measurement of human breast tumor cell-secreted shNDPK-B in a murine breast cancer model suggests its role in metastatic progression

27 July 2018

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A complex task? Direct modulation of transcription factors with small molecules

27 July 2018

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The landscape of somatic copy-number alteration across human cancers

27 July 2018

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Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein

27 July 2018

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Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

27 July 2018

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NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1

27 July 2018

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Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.

27 July 2018

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5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

27 July 2018

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Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray.

27 July 2018

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The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members

27 July 2018

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9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.

27 July 2018

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Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives

27 July 2018

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Targeting transcription factors for cancer gene therapy.

27 July 2018

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c-Myc as a therapeutic target in cancer

27 July 2018

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Transcription factors as targets for cancer therapy

27 July 2018

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Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

27 July 2018

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Peptidic determinants and structural model of human NDP kinase B (Nm23-H2) bound to single-stranded DNA.

27 July 2018

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Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit

27 July 2018

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NM23/Nucleoside diphosphate kinase as a transcriptional activator of c-myc

27 July 2018

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Nuclear localization of nucleoside diphosphate kinase type B (nm23-H2) in cultured cells

27 July 2018

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Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element

27 July 2018

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Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis

27 July 2018

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Nucleoside diphosphate kinase enzyme activity of NM23-H2/PuF is not required for its DNA binding and in vitro transcriptional functions

27 July 2018

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The crystal structure of a human nucleoside diphosphate kinase, NM23-H2

27 July 2018

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A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor.

27 July 2018

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DNA G-quadruplex binders: a patent review

27 July 2018

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Bcr-Abl dependent post-transcriptional activation of NME2 expression is a specific and common feature of chronic myeloid leukemia.

25 September 2018

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Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives.

25 September 2018

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Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA.

25 September 2018

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Quantitative structure-activity relationship analysis of 4(3H)-quinazolone derivatives as tyrosine kinase inhibitors by multiple linear regression

25 September 2018

1 reference

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Genome-wide computational and expression analyses reveal G-quadruplex DNA motifs as conserved cis-regulatory elements in human and related species.

25 September 2018

1 reference

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Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4538829

Human NM23/nucleoside diphosphate kinase regulates gene expression through DNA binding to nuclease-hypersensitive transcriptional elements

25 September 2018

1 reference

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Microscale thermophoresis for the assessment of nuclear protein-binding affinities

25 September 2018

1 reference

12 December 2020

Expression of human nm23-H1 and nm23-H2 proteins in hepatocellular carcinoma

1 reference

12 December 2020

PuF/NM23-H2/NDPK-B transactivates a human c-myc promoter-CAT gene via a functional nuclease hypersensitive element

1 reference

12 December 2020

Nm23/PuF does not directly stimulate transcription through the CT element in vivo

1 reference

12 December 2020

Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKV641

1 reference

9 August 2017

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9 August 2017

1 reference