Strategies to improve DNA polyplexes for in vivo gene transfer: will "artificial viruses" be the answer? (Q35675702)

9 August 2017

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title

Strategies to improve DNA polyplexes for in vivo gene transfer: will "artificial viruses" be the answer? (English)

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9 August 2017

Ernst Wagner

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9 August 2017

1 January 2004

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9 August 2017

Pharmaceutical Research

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9 August 2017

21

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9 August 2017

8-14

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9 August 2017

1

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Infectious poliovirus RNA: a sensitive method of assay

9 August 2017

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12 December 2020

Nonviral Gene Delivery to the Rat Kidney with Polyethylenimine

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12 December 2020

Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice

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12 December 2020

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle

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12 December 2020

Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine

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12 December 2020

Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake

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12 December 2020

Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity

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12 December 2020

A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

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12 December 2020

Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo

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12 December 2020

Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells

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12 December 2020

Enhancement of the plaque-forming capacity of poliovirus ribonucleic acid with basic proteins.

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12 December 2020

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini

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12 December 2020

Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver

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12 December 2020

Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier

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12 December 2020

Development of biomaterials for gene therapy

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12 December 2020

Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells

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12 December 2020

Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

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12 December 2020

Nomenclature for synthetic gene delivery systems.

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12 December 2020

Histidylated polylysine as DNA vector: elevation of the imidazole protonation and reduced cellular uptake without change in the polyfection efficiency of serum stabilized negative polyplexes

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12 December 2020

Receptor-mediated gene delivery and expression in vivo.

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12 December 2020

In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers

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12 December 2020

Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression

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12 December 2020

Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits

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12 December 2020

Low molecular weight disulfide cross-linking peptides as nonviral gene delivery carriers

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12 December 2020

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

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12 December 2020

The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration

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12 December 2020

Gene delivery with synthetic (non viral) carriers.

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12 December 2020

Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo

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12 December 2020

Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes

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12 December 2020

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

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12 December 2020

Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system

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12 December 2020

In vivo delivery to tumors of DNA complexed with linear polyethylenimine.

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12 December 2020

Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy

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12 December 2020

Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents.

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12 December 2020

Growth inhibition of established B16-F10 lung metastases by sequential aerosol delivery of p53 gene and 9-nitrocamptothecin

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12 December 2020

Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy.

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12 December 2020

Optimisation of polyethylenimine-based gene delivery to mouse brain.

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12 December 2020

A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle

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12 December 2020

Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer

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12 December 2020

Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse

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12 December 2020

Intranasal gene delivery with a polyethylenimine-PEG conjugate

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12 December 2020

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

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12 December 2020

Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

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12 December 2020

Cationic polymer based gene delivery systems

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12 December 2020

Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor

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12 December 2020

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo

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12 December 2020

Maximizing the in vivo efficiency of gene transfer by means of nonviral polymeric gene delivery vehicles

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12 December 2020

Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules

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12 December 2020

Biodegradable polyester, poly[alpha-(4-aminobutyl)-L-glycolic acid], as a non-toxic gene carrier

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12 December 2020

10.1023/B:PHAM.0000012146.04068.56

Identifiers

DOI

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9 August 2017

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PubMed ID

14984252