Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice (Q35650720)

9 August 2017

title

Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice (English)

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9 August 2017

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6

Laura P James

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9 August 2017

5

Sandra McCullough

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9 August 2017

Rakhee Agarwal

1

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9 August 2017

Leah Hennings

2

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9 August 2017

Tonya M Rafferty

3

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9 August 2017

Lynda G Letzig

4

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9 August 2017

Lee Ann MacMillan-Crow

7

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9 August 2017

Jack A Hinson

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9 August 2017

language of work or name

English

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publication date

14 October 2011

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Journal of Pharmacology and Experimental Therapeutics

9 August 2017

published in

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9 August 2017

volume

340

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9 August 2017

issue

1

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9 August 2017

page(s)

134-142

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Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.

9 August 2017

cites work

1 reference

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Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase

12 July 2018

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Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes

12 July 2018

1 reference

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Role of cytochrome P450 2E1 in protein nitration and ubiquitin-mediated degradation during acetaminophen toxicity

12 July 2018

1 reference

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Mitochondrial nitric oxide synthase

12 July 2018

1 reference

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Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

12 July 2018

1 reference

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Acetaminophen-induced hepatotoxicity

12 July 2018

1 reference

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The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

12 July 2018

1 reference

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Peroxisomal localization of inducible nitric oxide synthase in hepatocytes

12 July 2018

1 reference

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Invited review: manganese superoxide dismutase in disease

12 July 2018

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Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

12 July 2018

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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

12 July 2018

1 reference

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Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts

12 July 2018

1 reference

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Estimation of peroxidative damage. A critical review.

12 July 2018

1 reference

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N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

12 July 2018

1 reference

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Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

12 July 2018

1 reference

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Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

12 July 2018

1 reference

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Identification of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins.

12 July 2018

1 reference

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Ferrous ion supported in vivo lipid peroxidation induced by paracetamol--its relation to hepatotoxicity.

12 July 2018

1 reference

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Knockdown of superoxide dismutase 2 enhances acetaminophen-induced hepatotoxicity in rat.

12 July 2018

1 reference

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Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen

25 September 2018

1 reference

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How to protect against acetaminophen: don't ask for JUNK.

25 September 2018

1 reference

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Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251022

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251022

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251022

Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251022

Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251022

Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity.

25 September 2018

1 reference

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Mitochondrial nitric oxide synthase

25 September 2018

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

1 reference

12 December 2020

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

1 reference

12 December 2020

Freshly isolated hepatocytes as a model for studying the toxicity of paracetamol

1 reference

12 December 2020

Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver

1 reference

12 December 2020

Role of lipid peroxidation in acetaminophen-induced hepatotoxicity: comparison with carbon tetrachloride

1 reference

12 December 2020

Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes

1 reference

12 December 2020

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+

1 reference

12 December 2020

Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins

1 reference

12 December 2020

Evidence for a direct role of intracellular calcium in paracetamol toxicity

1 reference

12 December 2020

Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury

1 reference

12 December 2020

Acetaminophen-induced hepatic injury in mice: the role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.111.184192

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9 August 2017

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9 August 2017

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