Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction (Q35643329)

9 August 2017

Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction (English)

1 reference

(2R,3S,4S,5S)-4-[[(4R)-2-[(4R)-2-[2-[(2S,3R,4R,5S,6S,7R)-4,6-dihydroxy-2-methoxy-3,5,7-trimethyldecyl]-1,3-thiazol-4-yl]-4-methyl-5H-1,3-thiazol-4-yl]-4-methyl-5H-1,3-thiazole-4-carbonyl]amino]-3-hydroxy-2,5-dimethylheptanoic acid

9 August 2017

1 reference

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6

William H Gerwick

1 reference

9 August 2017

Karla L Malloy

1

1 reference

9 August 2017

Hyukjae Choi

2

1 reference

9 August 2017

Catherine Fiorilla

3

1 reference

9 August 2017

Fred A Valeriote

4

1 reference

9 August 2017

Teatulohi Matainaho

5

1 reference

9 August 2017

language of work or name

English

0 references

publication date

24 October 2011

1 reference

full work available at URL

9 August 2017

https://europepmc.org/articles/pmc3248991?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/j.bmcl.2011.10.054?email=unpaywall_01@example.com

published in

Bioorganic & Medicinal Chemistry Letters

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9 August 2017

22

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9 August 2017

1

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9 August 2017

683-688

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https://api.unpaywall.org/v2/10.1016/j.bmcl.2011.10.054?email=unpaywall_01@example.com

9 August 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

based on heuristic

inferred from online access status

cites work

The p53 pathway as a target in cancer therapeutics: obstacles and promise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Mdm2 facilitates the association of p53 with the proteasome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Inhibition of the p53-MDM2 interaction: targeting a protein-protein interface.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Mutations in the p53 gene occur in diverse human tumour types

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

The C terminus of p53 binds the N-terminal domain of MDM2.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Small-molecule inhibitors of MDM2 as new anticancer therapeutics

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Hexylitaconic acid: a new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248991

Total synthesis of hoiamide C

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22104152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22104152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2011.10.054

1 reference

9 August 2017

1 reference

9 August 2017

1 reference