New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments (Q35628128)

9 August 2017

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title

New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments (English)

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9 August 2017

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alcoholic liver disease

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Charles S Lieber

1

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9 August 2017

1 February 2004

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Current gastroenterology reports

9 August 2017

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9 August 2017

6

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9 August 2017

1

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9 August 2017

60-65

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https://scigraph.springernature.com/pub.10.1007/s11894-004-0027-0

9 August 2017

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Naltrexone in the treatment of alcohol dependence

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Prevention and treatment of liver fibrosis based on pathogenesis

21 January 2018

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Difference in Hepatic Metabolism of Long- and Medium-Chain Fatty Acids: the Role of Fatty Acid Chain Length in the Production of the Alcoholic Fatty Liver*

21 January 2018

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Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial

21 January 2018

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Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial

21 January 2018

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12 December 2020

Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes

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12 December 2020

Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

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12 December 2020

Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis

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12 December 2020

Differential depletion of carotenoids and tocopherol in liver disease

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12 December 2020

Carbohydrate-deficient transferrin and gamma-glutamyltransferase for the detection and monitoring of alcohol use: results from a multisite study

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12 December 2020

Decreased cytochrome oxidase activity in hepatic mitochondria after chronic ethanol consumption and the possible role of decreased cytochrome aa3 content and changes in phospholipids

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12 December 2020

II. Veterans Affairs Cooperative Study of Polyenylphosphatidylcholine in Alcoholic Liver Disease

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12 December 2020

Polyenylphosphatidylcholine attenuates non-alcoholic hepatic fibrosis and accelerates its regression.

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12 December 2020

Polyenylphosphatidylcholine attenuates alcohol-induced fatty liver and hyperlipemia in rats

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12 December 2020

S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon

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12 December 2020

A randomized trial of prednisolone in patients with severe alcoholic hepatitis

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12 December 2020

Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon

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12 December 2020

Risk factors of fibrosis in alcohol-induced liver disease

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12 December 2020

Lipocytes and transitional cells in alcoholic liver disease: A morphometric study

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12 December 2020

Colchicine in the treatment of cirrhosis of the liver.

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12 December 2020

Induction of cytochrome P-4502E1 by ethanol in rat Kupffer cells

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12 December 2020

Dilinoleoylphosphatidylcholine decreases hepatic stellate cell activation

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12 December 2020

I. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease: effects on drinking behavior by nurse/physician teams

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12 December 2020

Polyunsaturated phosphatidyl-choline and interferon alpha for treatment of chronic hepatitis B and C: a multi-center, randomized, double-blind, placebo-controlled trial. Leich Study Group.

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12 December 2020

Acetaldehyde and lactate stimulate collagen synthesis of cultured baboon liver myofibroblasts

1 reference

12 December 2020

Silymarin Retards the Progression of Alcohol-Induced Hepatic Fibrosis in Baboons

1 reference

12 December 2020

Decreased tumor necrosis factor-alpha and interleukin-1alpha production from intrahepatic mononuclear cells in chronic ethanol consumption and upregulation by endotoxin

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12 December 2020

Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1.

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12 December 2020

Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease

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12 December 2020

Alcoholic liver injury: pathogenesis and therapy in 2001.

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12 December 2020

Collagen synthesis by liver stellate cells is released from its normal feedback regulation by acetaldehyde-induced modification of the carboxyl-terminal propeptide of procollagen

1 reference

12 December 2020

Hepatic Phosphatidylethanolamine Methyltransferase Activity Is Decreased by Ethanol and Increased by Phosphatidylcholine

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12 December 2020

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1 reference

12 December 2020

Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism.

1 reference

12 December 2020

Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease

1 reference

12 December 2020

Glucocorticoids are ineffective in alcoholic hepatitis: a meta-analysis adjusting for confounding variables

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12 December 2020

Dilinoleoylphosphatidylcholine selectively modulates lipopolysaccharide-induced Kupffer cell activation

1 reference

12 December 2020

S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.

1 reference

12 December 2020

Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes

1 reference

12 December 2020

Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells

1 reference

12 December 2020

Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients

1 reference

12 December 2020

Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver

1 reference

12 December 2020

Effects of long-term vitamin E supplementation in alcoholic cirrhotics

1 reference

12 December 2020

Ethanol induces transforming growth factor-alpha expression in hepatocytes, leading to stimulation of collagen synthesis by hepatic stellate cells

1 reference

12 December 2020

Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial.

1 reference

12 December 2020

Alcoholic liver disease: new insights in pathogenesis lead to new treatments

1 reference

12 December 2020

DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells

1 reference

12 December 2020

Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study

1 reference

12 December 2020

Short- and long-term outcome of severe alcohol-induced hepatitis treated with steroids or enteral nutrition: a multicenter randomized trial

1 reference

12 December 2020

Cytochrome P-4502E1: its physiological and pathological role

1 reference

12 December 2020

10.1007/S11894-004-0027-0

Identifiers

DOI

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9 August 2017

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PubMed ID

14720455