Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine ileitis (Q35627709)

25637591

9 August 2017

title

Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine ileitis (English)

1 reference

9 August 2017

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1

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1 June 2020

author name string

Joanne C Masterson

2

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1 June 2020

Marisol Veny

3

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1 June 2020

Colm B Collins

4

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1 June 2020

Paul Jedlicka

5

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1 June 2020

Fergus R Byrne

6

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1 June 2020

Gordon Y Ng

7

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1 June 2020

Jesús Rivera-Nieves

8

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1 June 2020

language of work or name

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30 January 2015

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25637591

Journal of Leukocyte Biology

9 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25637591%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

97

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1 June 2020

issue

6

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1 June 2020

page(s)

1011-1022

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Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes

1 June 2020

cites work

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Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation

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Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells.

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Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis

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27 July 2018

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Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis.

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Novel model of TH2-polarized chronic ileitis: the SAMP1 mouse.

27 July 2018

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CD44 deficiency attenuates chronic murine ileitis

27 July 2018

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CCR7 and its ligands: balancing immunity and tolerance

27 July 2018

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Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

27 July 2018

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Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue

27 July 2018

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CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells

27 July 2018

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Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

27 July 2018

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Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanism

27 July 2018

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Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

27 July 2018

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CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells

27 July 2018

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Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation

27 July 2018

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27 July 2018

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CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

27 July 2018

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Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization

27 July 2018

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CCR7 plays no appreciable role in trafficking of central memory CD4 T cells to lymph nodes.

27 July 2018

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Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells

25 September 2018

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Flt3 ligand expands CD103⁺ dendritic cells and FoxP3⁺ T regulatory cells, and attenuates Crohn's-like murine ileitis

25 September 2018

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Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients.

25 September 2018

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25 September 2018

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25 September 2018

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Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.

25 September 2018

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25 September 2018

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

25 September 2018

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25 September 2018

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CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.

25 September 2018

1 reference

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Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

25 September 2018

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25 September 2018

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Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

25 September 2018

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In vivo differentiated cytokine-producing CD4(+) T cells express functional CCR7.

25 September 2018

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Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma

25 September 2018

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Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses

25 September 2018

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Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo

25 September 2018

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12 December 2020

A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity

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12 December 2020

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

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Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes

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Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

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The lymphoid chemokine CCL21 costimulates naive T cell expansion and Th1 polarization of non-regulatory CD4+ T cells

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A passport into the lymph node

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Experimental autoimmune encephalomyelitis develops in CC chemokine receptor 7-deficient mice with altered T-cell responses

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Identifiers

DOI

10.1189/JLB.3HI0614-303R

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25637591%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25637591%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25637591

1 reference