Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2. (Q35621118)

9 August 2017

title

Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2. (English)

1 reference

9 August 2017

Madhu Mahankali

1

1 reference

9 August 2017

Hong-Juan Peng

2

1 reference

9 August 2017

Karen M Henkels

3

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9 August 2017

Mary C Dinauer

4

1 reference

9 August 2017

Julian Gomez-Cambronero

5

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9 August 2017

language of work or name

English

0 references

publication date

21 November 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

108

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9 August 2017

issue

49

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9 August 2017

page(s)

19617-19622

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The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis

9 August 2017

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Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2.

12 July 2018

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Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.

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Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42

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The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

12 July 2018

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Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species

12 July 2018

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12 July 2018

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Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase

12 July 2018

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Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

12 July 2018

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A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

12 July 2018

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Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox)

12 July 2018

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12 July 2018

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12 July 2018

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A cytosolic protein catalyzes the release of GDP from p21ras

12 July 2018

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Purification of a factor capable of stimulating the guanine nucleotide exchange reaction of ras proteins and its effect on ras-related small molecular mass G proteins

12 July 2018

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Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins

12 July 2018

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

12 July 2018

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Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

12 July 2018

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25 September 2018

Identifiers

DOI

10.1073/PNAS.1114692108

1 reference

9 August 2017

0 references

1 reference

9 August 2017

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