Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination. (Q35612355)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17210914%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

title

Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination (English)

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23 December 2019

1

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23 December 2019

author name string

Michael S Krangel

series ordinal

2

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23 December 2019

language of work or name

English

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publication date

8 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17210914%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 December 2019

published in

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23 December 2019

volume

104

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23 December 2019

issue

3

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23 December 2019

page(s)

903-907

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Revision of T cell receptor {alpha} chain genes is required for normal T lymphocyte development.

23 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters

27 July 2018

1 reference

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Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Gene segment selection in V(D)J recombination: accessibility and beyond

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

The mechanism and regulation of chromosomal V(D)J recombination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Requirement for RORgamma in thymocyte survival and lymphoid organ development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

A role for histone acetylation in the developmental regulation of VDJ recombination.

27 July 2018

1 reference

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Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

Exclusion and inclusion of α and β T cell receptor alleles

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783412

The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo

27 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0608248104

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0608248104

Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0608248104

Regulation of T cell receptor-alpha gene recombination by transcription

21 January 2018

1 reference

12 December 2020

Ordered and coordinated rearrangement of the TCR alpha locus: role of secondary rearrangement in thymic selection

1 reference

12 December 2020

T early alpha (TEA) regulates initial TCRVAJA rearrangements and leads to TCRJA coincidence

1 reference

12 December 2020

TEA regulates local TCR-Jalpha accessibility through histone acetylation

1 reference

12 December 2020

First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5' region of the J alpha locus

1 reference

12 December 2020

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0608248104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17210914%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17210914%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

1 reference