DNA methylation in haematological malignancies: the role of decitabine (Q35594048)

9 August 2017

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title

DNA methylation in haematological malignancies: the role of decitabine (English)

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9 August 2017

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3

Hagop M Kantarjian

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PubMed ID

14640942

9 August 2017

Guillermo Garcia-Manero

series ordinal

2

object named as

Guillermo Garcia-Manero

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9 August 2017

1

Bryan T Hennessy

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9 August 2017

4

Francis J Giles

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PubMed ID

14640942

9 August 2017

language of work or name

English

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publication date

1 December 2003

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Expert Opinion on Investigational Drugs

9 August 2017

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9 August 2017

12

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9 August 2017

12

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9 August 2017

1985-1993

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DNA methylation and cancer

9 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

New drugs in acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

A mammalian protein with specific demethylase activity for mCpG DNA.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

G1 cyclins and control of the cell division cycle in normal and transformed cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Analysis of promoter hypermethylation of death-associated protein kinase and p16 tumor suppressor genes in actinic keratoses and squamous cell carcinomas of the skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

P15INK4b gene methylation and myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

PTEN methylation and expression in glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Suppression of gap junctional intercellular communication via 5' CpG island methylation in promoter region of E-cadherin gene in endometrial cancer cells.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Methylation and silencing of the Thrombospondin-1 promoter in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Methylation profiling in acute myeloid leukemia.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Altered methylation of multiple genes in carcinogenesis of the prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Aberrant DNA methylation in pediatric patients with acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2'-deoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16INK4A RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

Chronic myelogenous leukemia in nonlymphoid blastic phase: analysis of the results of first salvage therapy with three different treatment approaches for 162 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

DNA methylation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.12.1985

10.1517/13543784.12.12.1985

21 January 2018

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14640942