Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy. (Q35566610)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25441634%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy (English)

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23 February 2020

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13

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23 February 2020

Richard Weiss

14

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23 February 2020

Peter Valent

17

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23 February 2020

Katarzyna Niespodziana

3

object named as

Katarzyna Niespodziana

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23 February 2020

author name string

Margarete Focke-Tejkl

1

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23 February 2020

Milena Weber

2

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23 February 2020

Angela Neubauer

4

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23 February 2020

Hans Huber

5

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23 February 2020

Rainer Henning

6

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23 February 2020

Gottfried Stegfellner

7

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23 February 2020

Bernhard Maderegger

8

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23 February 2020

Martina Hauer

9

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23 February 2020

Frank Stolz

10

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23 February 2020

Verena Niederberger

11

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23 February 2020

Katharina Marth

12

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23 February 2020

Josef Thalhamer

15

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23 February 2020

Katharina Blatt

16

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23 February 2020

Rudolf Valenta

18

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23 February 2020

language of work or name

English

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publication date

13 November 2014

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The Journal of Allergy and Clinical Immunology

23 February 2020

published in

1 reference

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23 February 2020

volume

135

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23 February 2020

issue

5

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23 February 2020

page(s)

1207-7.e1-11

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Conversion of Der p 23, a new major house dust mite allergen, into a hypoallergenic vaccine.

23 February 2020

cites work

1 reference

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Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5.

12 July 2018

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12 July 2018

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A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1 phenotype

12 July 2018

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12 July 2018

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One hundred years of allergen immunotherapy European Academy of Allergy and Clinical Immunology celebration: review of unanswered questions.

12 July 2018

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Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivatives

12 July 2018

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12 July 2018

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Induction of allergen-specific tolerance via mucosal routes.

12 July 2018

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Recombinant allergens: what does the future hold?

12 July 2018

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Vaccine approaches for food allergy

12 July 2018

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Recombinant allergens for allergen-specific immunotherapy: 10 years anniversary of immunotherapy with recombinant allergens

12 July 2018

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Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules

12 July 2018

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High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography

12 July 2018

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CD200R surface expression as a marker of murine basophil activation

12 July 2018

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Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy

12 July 2018

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Immunological mechanisms of allergen-specific immunotherapy

12 July 2018

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Comparative immunogenicity of a PreS/S hepatitis B vaccine in non- and low responders to conventional vaccine

12 July 2018

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Vaccination with genetically engineered allergens prevents progression of allergic disease.

12 July 2018

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Characteristics and immunobiology of grass pollen allergens.

12 July 2018

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Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).

12 July 2018

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An immunoglobulin-like fold in a major plant allergen: the solution structure of Phl p 2 from timothy grass pollen

12 July 2018

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Long-term clinical efficacy of grass-pollen immunotherapy

12 July 2018

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Molecular characterization of Phl p II, a major timothy grass (Phleum pratense) pollen allergen.

12 July 2018

1 reference

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cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen; characterization of the recombinant Phl pV allergen.

12 July 2018

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Studies on the effect of the carrier molecule on antihapten antibody synthesis. I. Effect of carrier on the nature of the antibody synthesized

12 July 2018

1 reference

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Epidemiology of emergency room asthma in northern California: association with IgE antibody to ryegrass pollen

12 July 2018

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Profilins constitute a novel family of functional plant pan-allergens.

12 July 2018

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A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS.

12 July 2018

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A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1.

26 September 2018

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Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein

26 September 2018

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Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.

26 September 2018

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26 September 2018

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Recombinant allergens promote expression of CD203c on basophils in sensitized individuals

26 September 2018

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Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination.

26 September 2018

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26 September 2018

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IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens.

26 September 2018

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26 September 2018

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Allergen-specific immunotherapy with recombinant allergens

7 December 2018

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Specific subcutaneous immunotherapy with recombinant grass pollen allergens: first randomized dose-ranging safety study

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What are the important allergens in grass pollen that are linked to human allergic disease?

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Clinical effects of hyposensitization using a purified allergen preparation from Timothy pollen as compared to crude aqueous extracts from Timothy pollen and a four-grass pollen mixture respectively

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Allergen-specific immunotherapy with recombinant grass pollen allergens

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Side-effects of allergen-specific immunotherapy: a prospective multi-centre study

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Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis

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IgE antibodies to recombinant pollen allergens (Phl p 1, Phl p 2, Phl p 5, and Bet v 2) account for a high percentage of grass pollen-specific IgE

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Different allergenic activity of grass pollen allergens revealed by skin testing

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Heterogeneity of commercial timothy grass pollen extracts

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Developments in allergen-specific immunotherapy: from allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivity

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Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies

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Recombinant allergens for specific immunotherapy

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Immunotherapy concepts under investigation

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12 December 2020

10.1016/J.JACI.2014.09.012

Identifiers

DOI

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23 February 2020

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23 February 2020

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