The prodigiosins, proapoptotic drugs with anticancer properties (Q35557610)

8 August 2017

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title

The prodigiosins, proapoptotic drugs with anticancer properties (English)

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8 August 2017

Vanessa Soto-Cerrato

4

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Beatriz Montaner

object named as

Beatriz Montaner

series ordinal

2

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Ricardo Pérez-Tomás

object named as

Ricardo Pérez-Tomás

series ordinal

1

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Esther Llagostera

series ordinal

3

object named as

Esther Llagostera

1 reference

PubMed ID

14555220

8 August 2017

language of work or name

English

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publication date

1 October 2003

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8 August 2017

Biochemical Pharmacology

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8 August 2017

66

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8 August 2017

8

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8 August 2017

1447-1452

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Seeing red: The story of prodigiosin

8 August 2017

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Tumours and Coley's toxins

7 January 2021

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An endotoxin-induced serum factor that causes necrosis of tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Antimalarial Activity of Prodigiosin

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cycloprodigiosin hydrochloride obtained from Pseudoalteromonas denitrificans is a potent antimalarial agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cytotoxicity of prodigiosin and benznidazole on V79 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Selective suppression by prodigiosin of the mitogenic response of murine splenocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Suppression of cytotoxic T cell induction in vivo by prodigiosin 25-C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Immunomodulating properties of prodigiosin 25-C, an antibiotic which preferentially suppresses induction of cytotoxic T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosin 25-C suppression of cytotoxic T cells in vitro and in vivo similar to that of concanamycin B, a specific inhibitor of vacuolar type H(+)-ATPase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Effect of metacycloprodigiosin, an inhibitor of killer T cells on murine skin and heart transplants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

A possible immunosuppressant, cycloprodigiosin hydrochloride, obtained from Pseudoalteromonas denitrificans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

T-cell specific immunosuppression by prodigiosin isolated from Serratia marcescens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Suppression of T cell stimulating function of allogeneic antigen presenting cells by prodigiosin 25-C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

In vivo rapid reduction of alloantigen-activated CD8+ mature cytotoxic T cells by inhibitors of acidification of intracellular organelles, prodigiosin 25-C and concanamycin B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Induction of apoptosis of activated murine splenic T cells by cycloprodigiosin hydrochloride, a novel immunosuppressant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cycloprodigiosin hydrochloride as an immunosuppressant in rat small bowel transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in haematopoietic cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosin-induced apoptosis in human colon cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Synthesis and immunosuppressive activity of novel prodigiosin derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cycloprodigiosin hydrochloride, a H+/Cl- symporter, induces apoptosis in human breast cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cycloprodigiosin hydrochloride, H(+)/CL(-) symporter, induces apoptosis and differentiation in HL-60 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Cycloprodigiosin hydrochloride, a new H(+)/Cl(-) symporter, induces apoptosis in human and rat hepatocellular cancer cell lines in vitro and inhibits the growth of hepatocellular carcinoma xenografts in nude mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosins as a new group of H+/Cl- symporters that uncouple proton translocators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Demonstration of Cl- requirement for inhibition of vacuolar acidification by cycloprodigiosin in situ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosins uncouple mitochondrial and bacterial F-ATPases: evidence for their H+/Cl- symport activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Prodigiosin 25-C uncouples vacuolar type H(+)-ATPase, inhibits vacuolar acidification and affects glycoprotein processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Role of intracellular pH in proliferation, transformation, and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Tumor-suppressor p53: implications for tumor development and prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

DNA Binding by 4-Methoxypyrrolic Natural Products. Preference for Intercalation at AT Sites by Tambjamine E and Prodigiosin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Copper transport and its defect in Wilson disease: characterization of the copper-binding domain of Wilson disease ATPase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Copper and carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Copper-nuclease efficiency correlates with cytotoxicity for the 4-methoxypyrrolic natural products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Influence of the a-ring on the redox and nuclease properties of the prodigiosins: importance of the bipyrrole moiety in oxidative DNA cleavage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

DNA double-strand breaks: signaling, repair and the cancer connection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Parallel signal processing among mammalian MAPKs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Tumor necrosis factor mediates apoptosis via Ca++/Mg++ dependent endonuclease with protein kinase C as a possible mechanism for cytokine resistance in human renal carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Inhibition of radiation-induced apoptosis in vitro by tumor promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

Activation of protein kinase C for protection of cells against apoptosis induced by the immunosuppressor prodigiosin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

The cytotoxic prodigiosin induces phosphorylation of p38-MAPK but not of SAPK/JNK.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900496-9

10.1016/S0006-2952(03)00496-9

7 January 2021

Identifiers

DOI

1 reference

8 August 2017

1 reference

PubMed ID

14555220