Targeted therapy of solid malignancies via HLA class II antigens: a new biotherapeutic approach? (Q35551133)

8 August 2017

Targeted therapy of solid malignancies via HLA class II antigens: a new biotherapeutic approach? (English)

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8 August 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1206960

18 March 2024

3

Alberto Visintin

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8 August 2017

Maresa Altomonte

1

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8 August 2017

Ester Fonsatti

2

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8 August 2017

Michele Maio

4

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8 August 2017

language of work or name

English

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publication date

1 September 2003

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8 August 2017

29 September 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14528281

full work available at URL

18 March 2024

https://www.nature.com/articles/1206960.pdf

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/SJ.ONC.1206960

https://www.nature.com/articles/1206960

18 March 2024

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https://api.crossref.org/works/10.1038/SJ.ONC.1206960

18 March 2024

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8 August 2017

22

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8 August 2017

42

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8 August 2017

6564-6569

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206960

8 August 2017

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On the biological relevance of MHC class II and B7 expression by tumour cells in melanoma metastases.

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Class II transactivator regulates the expression of multiple genes involved in antigen presentation

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Expression of HLA-DR antigen in large bowel carcinoma

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HLA-DR and beta 2 microglobulin expression in medullary and atypical medullary carcinoma of the breast: histopathologically similar but biologically distinct entities

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HLA class I and class II antigen expression on squamous cell carcinoma of the head and neck

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CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system

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The bare lymphocyte syndrome and the regulation of MHC expression

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A listing of human tumor antigens recognized by T cells

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Long-term prognostic significance of HSP-70, c-myc and HLA-DR expression in patients with malignant melanoma

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Is heterogeneous expression of HLA-dr antigens and CEA along with DNA-profile variations evidence of phenotypic instability and clonal proliferation in human large bowel carcinomas?

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Evaluation of HLA-DR expression and T-lymphocyte infiltration in osteosarcoma.

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An immunohistochemical study of altered immunomodulatory molecule expression in head and neck squamous cell carcinoma

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Lacking prognostic significance of beta 2-microglobulin, MHC class I and class II antigen expression in breast carcinomas

21 January 2018

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Lack of class II transactivator causes severe deficiency of HLA-DR expression in small cell lung cancer

21 January 2018

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Immunohistochemical analysis of HLA antigens and mononuclear infiltrates of benign and malignant breast

21 January 2018

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Distinct structural compartmentalization of the signal transducing functions of major histocompatibility complex class II (Ia) molecules

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7 January 2021

Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins

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7 January 2021

HLA-DR antigens on differentiating human mammary gland epithelium and breast tumours

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7 January 2021

Expression of HLA-D subloci DR and DQ by breast carcinomas is correlated with distinct parameters of favourable prognosis

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7 January 2021

High levels of Fas ligand and MHC class II in the absence of CD80 or CD86 expression and a decreased CD4+ T cell Infiltration, enables murine skin tumours to progress

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7 January 2021

Biological implications of HLA-DR expression in tumours

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7 January 2021

Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction

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7 January 2021

Chimeric IgA antibodies against HLA class II effectively trigger lymphoma cell killing

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7 January 2021

Histocompatibility antigens in primary and metastatic squamous cell carcinoma of the larynx

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7 January 2021

The cytoplasmic and transmembrane domains of MHC class II β chains deliver distinct signals required for MHC class II-mediated B cell activation

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7 January 2021

An evaluation of the prognostic significance of HLA-DR expression in gastric carcinoma

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7 January 2021

Mononuclear cells infiltrating human mammary carcinomas: immunohistochemical analysis with monoclonal antibodies

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7 January 2021

Prognostic value of HLA-DR expression and dendritic cell infiltration in gastric cancer

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7 January 2021

The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes

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7 January 2021

Correlation of HLA-D/Ii antigen expression in breast carcinoma with local lymphohistiocytic infiltration reveals considerable dysregulation in a subset of tumors

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7 January 2021

Combined expression of HLA-DR antigen and proliferating cell nuclear antigen correlate with colorectal cancer prognosis.

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7 January 2021

Heat shock protein 70 and HLA-DR molecules tissue expression. Prognostic implications in colorectal cancer

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7 January 2021

Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis

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7 January 2021

IFN-gamma inducibility of class II transactivator is specifically lacking in human tumour lines: relevance to retinoblastoma protein rescue of IFN-gamma inducibility of the HLA class II genes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Prognostic significance of T-cell infiltrates, expression of beta 2-microglobulin and HLA-DR antigens in breast carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Expression of HLA-class II antigen in gastric carcinomas. Its relationship to histopathological grade, lymphocyte infiltration and five-year survival rate

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7 January 2021

Differential modulation by tumor necrosis factor and immune interferon of HLA class-II antigens expressed by melanoma cells

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7 January 2021

HLA antigen expression in routinely processed head and neck squamous cell carcinoma primary lesions of different sites

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7 January 2021

Immunohistochemically demonstrated expression of HLA-DR antigen in colorectal adenocarcinomas and its relation to clinicopathological features

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7 January 2021

Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

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7 January 2021

Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Strong HLA-DR expression in large bowel carcinomas is associated with good prognosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Can immunohistochemical markers and mitotic rate improve prognostic precision in patients with primary melanoma?

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Prognostic immunohistochemical markers of primary human melanomas

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7 January 2021

Heterogeneity of the expression of class I and II HLA antigens in human breast carcinoma

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7 January 2021

Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins

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7 January 2021

Local immune response to tumor invasion in esophageal squamous cell carcinoma. The expression of human leukocyte antigen-DR and lymphocyte infiltration.

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7 January 2021

MHC class II antigen-associated invariant chain on renal cell cancer may contribute to the anti-tumor immune response of the host

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

MHC class II signaling in B-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Expression of the neuroglandular antigen and analogues in melanoma. CD9 expression appears inversely related to metastatic potential of melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Enhanced killing of B lymphoma cells by granulocyte colony-stimulating factor-primed effector cells and Hu1D10--a humanized human leucocyte antigen DR antibody

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

HLA class II molecule signal transduction leads to either apoptosis or activation via two different pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Structural compartmentalization of MHC class II signaling function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Complicated mechanisms of class II transactivator transcription deficiency in small cell lung cancer and neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

HLA class II sublocus expression in benign and malignant breast epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206960

7 January 2021

Can the HLA phenotype be used as a prognostic factor in breast carcinomas?

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https://api.crossref.org/works/10.1038/SJ.ONC.1206960

Altered HLA expression by metastatic cervical carcinoma cells as a factor in impaired immune surveillance

18 March 2024

29

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https://api.crossref.org/works/10.1038/SJ.ONC.1206960

18 March 2024

Identifiers

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8 August 2017

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