Complexity and challenges in defining myeloid-derived suppressor cells (Q35509317)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25504825%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

review article

3 references

27 October 2020

3 December 2020

Complexity and challenges in defining myeloid-derived suppressor cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25504825%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

12 October 2019

1 reference

27 October 2020

1 reference

3 December 2020

1

1 reference

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25 February 2020

Laura Pinton

2

1 reference

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25 February 2020

Samantha Solito

4

1 reference

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25 February 2020

Susanna Mandruzzato

7

1 reference

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25 February 2020

author name string

Giacomo Desantis

3

1 reference

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25 February 2020

Ilaria Marigo

5

1 reference

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25 February 2020

Vincenzo Bronte

6

1 reference

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25 February 2020

publication date

12 December 2014

1 reference

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25 February 2020

1 March 2015

2 references

27 October 2020

3 December 2020

15

1 reference

Cytometry Part B: Clinical Cytometry

inferred from page(s)

published in

5 references

30 June 2019

12 October 2019

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25 February 2020

27 October 2020

3 December 2020

88

1 reference

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25 February 2020

issue

2

1 reference

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25 February 2020

page(s)

77-91

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

25 February 2020

copyright license

4 references

30 June 2019

12 October 2019

27 October 2020

Myeloid-derived suppressor cell heterogeneity in human cancers

3 December 2020

cites work

1 reference

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Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma

12 July 2018

1 reference

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CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs.

12 July 2018

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Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes

12 July 2018

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The cellular and molecular origin of tumor-associated macrophages

12 July 2018

1 reference

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Myeloid-derived suppressor cells in cancer: therapeutic, predictive, and prognostic implications

12 July 2018

1 reference

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Untreated stage IV melanoma patients exhibit abnormal monocyte phenotypes and decreased functional capacity

12 July 2018

1 reference

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Increased levels of granulocytic myeloid-derived suppressor cells in peripheral blood and tumour tissue of pancreatic cancer patients

12 July 2018

1 reference

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Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer.

12 July 2018

1 reference

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The emerging immunological role of post-translational modifications by reactive nitrogen species in cancer microenvironment

12 July 2018

1 reference

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Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab

12 July 2018

1 reference

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GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α.

12 July 2018

1 reference

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Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2.

12 July 2018

1 reference

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Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

12 July 2018

1 reference

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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

12 July 2018

1 reference

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Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer

12 July 2018

1 reference

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Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma

12 July 2018

1 reference

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Critical assessment of automated flow cytometry data analysis techniques.

12 July 2018

1 reference

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Increased level of myeloid-derived suppressor cells, programmed death receptor ligand 1/programmed death receptor 1, and soluble CD25 in Sokal high risk chronic myeloid leukemia

12 July 2018

1 reference

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Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.

12 July 2018

1 reference

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Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans

12 July 2018

1 reference

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Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

12 July 2018

1 reference

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Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

12 July 2018

1 reference

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Highlights on molecular mechanisms of MDSC-mediated immune suppression: paving the way for new working hypotheses.

12 July 2018

1 reference

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Immune tolerance to tumor antigens occurs in a specialized environment of the spleen

12 July 2018

1 reference

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CD14(+)S100A9(+) monocytic myeloid-derived suppressor cells and their clinical relevance in non-small cell lung cancer

12 July 2018

1 reference

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Deciphering the transcriptional network of the dendritic cell lineage

12 July 2018

1 reference

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Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma

12 July 2018

1 reference

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Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

12 July 2018

1 reference

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Tumor-induced myeloid-derived suppressor cell function is independent of IFN-γ and IL-4Rα.

12 July 2018

1 reference

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Impact of human granulocyte and monocyte isolation procedures on functional studies

12 July 2018

1 reference

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Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples

12 July 2018

1 reference

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Coordinated regulation of myeloid cells by tumours

12 July 2018

1 reference

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Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils

12 July 2018

1 reference

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Origins of tumor-associated macrophages and neutrophils.

12 July 2018

1 reference

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Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression

12 July 2018

1 reference

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Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth.

12 July 2018

1 reference

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PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment

12 July 2018

1 reference

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Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

12 July 2018

1 reference

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Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

12 July 2018

1 reference

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A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

12 July 2018

1 reference

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MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

12 July 2018

1 reference

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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

12 July 2018

1 reference

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Control of immune response by amino acid metabolism

12 July 2018

1 reference

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Data analysis in flow cytometry: the future just started

12 July 2018

1 reference

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Unravelling mononuclear phagocyte heterogeneity

12 July 2018

1 reference

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Macrophage diversity enhances tumor progression and metastasis

12 July 2018

1 reference

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Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.

12 July 2018

1 reference

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Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer

12 July 2018

1 reference

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

12 July 2018

1 reference

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Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism.

12 July 2018

1 reference

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Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes

12 July 2018

1 reference

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Myeloid-derived suppressor cells as regulators of the immune system

12 July 2018

1 reference

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Subsets of myeloid-derived suppressor cells in tumor-bearing mice

12 July 2018

1 reference

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High-sensitivity immunofluorescence/flow cytometry: detection of cytokine receptors and other low-abundance membrane molecules

12 July 2018

1 reference

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Mononuclear myeloid-derived "suppressor" cells express RAE-1 and activate natural killer cells

12 July 2018

1 reference

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Standardization and optimization of multiparameter intracellular cytokine staining

12 July 2018

1 reference

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A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells

12 July 2018

1 reference

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Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

12 July 2018

1 reference

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Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

12 July 2018

1 reference

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Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Optimizing a multicolor immunophenotyping assay

12 July 2018

1 reference

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Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Altered macrophage differentiation and immune dysfunction in tumor development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Chitin induces accumulation in tissue of innate immune cells associated with allergy

12 July 2018

1 reference

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The terminology issue for myeloid-derived suppressor cells

12 July 2018

1 reference

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Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

12 July 2018

1 reference

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CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells

12 July 2018

1 reference

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Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Regulation of immune responses by L-arginine metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.

12 July 2018

1 reference

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Single cell profiling of potentiated phospho-protein networks in cancer cells.

12 July 2018

1 reference

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Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Derangement of immune responses by myeloid suppressor cells

12 July 2018

1 reference

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An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice

12 July 2018

1 reference

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Immature myeloid cells and cancer-associated immune suppression

12 July 2018

1 reference

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Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

12 July 2018

1 reference

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Tumor-induced immune dysfunctions caused by myeloid suppressor cells

12 July 2018

1 reference

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Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocyte-macrophage colony-stimulating factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Treatment with lenalidomide induces immunoactivating and counter-regulatory immunosuppressive changes in myeloma patients.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Increase in CD14+HLA-DR -/low myeloid-derived suppressor cells in hepatocellular carcinoma patients and its impact on prognosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Increased myeloid-derived suppressor cells in gastric cancer correlate with cancer stage and plasma S100A8/A9 proinflammatory proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colony-stimulating factors in head and neck cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Flow cytometric determination of stem/progenitor content in epithelial tissues: an example from nonsmall lung cancer and normal lung

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Immunosuppressive CD14+HLA-DRlow/neg IDO+ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Immunosuppressive CD14+HLA-DR(low)/- monocytes in B-cell non-Hodgkin lymphoma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Analysis of splenic Gr-1int immature myeloid cells in tumor-bearing mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Immunophenotypic differentiation patterns of normal hematopoiesis in human bone marrow: reference patterns for age-related changes and disease-induced shifts

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405078

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCYTO.B.21206

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCYTO.B.21206

Increased Level of both CD4+FOXP3+ Regulatory T Cells and CD14+HLA-DR−/low Myeloid-Derived Suppressor Cells and Decreased Level of Dendritic Cells in Patients with Multiple Myeloma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FCYTO.B.21206

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

21 January 2018

1 reference

12 December 2020

Measurement of myeloid cell immune suppressive activity

1 reference

12 December 2020

Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies

1 reference

12 December 2020

Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14⁻/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer

1 reference

12 December 2020

Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells

1 reference

12 December 2020

Comparison of monocyte-dependent T cell inhibitory activity in GM-CSF vs G-CSF mobilized PSC products

1 reference

12 December 2020

STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion

1 reference

12 December 2020

Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma

1 reference

12 December 2020

Titration of fluorochrome-conjugated antibodies for labeling cell surface markers on live cells

1 reference

12 December 2020

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

1 reference

12 December 2020

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

12 December 2020

Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation

1 reference

12 December 2020

Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer

1 reference

12 December 2020

Reduced expression of distinct T-cell CD molecules by collagenase/DNase treatment

1 reference

12 December 2020

Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign

1 reference

12 December 2020

Monocytes from mobilized stem cells inhibit T cell function

1 reference

12 December 2020

Suppression of alloantigen-induced T-cell proliferation by CD14+ cells derived from granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells

1 reference

12 December 2020

Identifiers

DOI

10.1002/CYTO.B.21206

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25504825%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25504825%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference