CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells (Q35500089)

8 August 2017

CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells (English)

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8 August 2017

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Yan Li

1

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8 August 2017

Chloe M Rivera

2

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8 August 2017

Haruhiko Ishii

3

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8 August 2017

Fulai Jin

4

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8 August 2017

Siddarth Selvaraj

5

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8 August 2017

Ah Young Lee

6

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8 August 2017

Jesse R Dixon

7

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8 August 2017

Bing Ren

8

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8 August 2017

language of work or name

English

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publication date

8 December 2014

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8 August 2017

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8 August 2017

9

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8 August 2017

e114485

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8 August 2017

12

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Creative Commons Attribution 4.0 International

8 August 2017

start time

8 December 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

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Super-enhancers in the control of cell identity and disease

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Architectural protein subclasses shape 3D organization of genomes during lineage commitment

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Master transcription factors and mediator establish super-enhancers at key cell identity genes

27 July 2018

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The sox family of transcription factors: versatile regulators of stem and progenitor cell fate

27 July 2018

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RNA-guided human genome engineering via Cas9

27 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

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Master transcription factors determine cell-type-specific responses to TGF-β signaling

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Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice

27 July 2018

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PU.1 and C/EBP(alpha) synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers

27 July 2018

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Enhancer function: new insights into the regulation of tissue-specific gene expression

27 July 2018

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Functional and mechanistic diversity of distal transcription enhancers

27 July 2018

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A unique chromatin signature uncovers early developmental enhancers in humans

27 July 2018

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Histone H3K27ac separates active from poised enhancers and predicts developmental state

27 July 2018

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Distinct epigenomic landscapes of pluripotent and lineage-committed human cells.

27 July 2018

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The transcriptional foundation of pluripotency

27 July 2018

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The polycomb group protein Suz12 is required for embryonic stem cell differentiation

27 July 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

27 July 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

27 July 2018

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Scanning Human Gene Deserts for Long-Range Enhancers

27 July 2018

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Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization

27 July 2018

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Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells

27 July 2018

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SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.

27 July 2018

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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

26 September 2018

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Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

26 September 2018

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

26 September 2018

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A map of the cis-regulatory sequences in the mouse genome

26 September 2018

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Enhancers: multi-dimensional signal integrators

26 September 2018

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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259346

Polycomb complexes repress developmental regulators in murine embryonic stem cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259346

10.1371/JOURNAL.PONE.0114485

26 September 2018

Identifiers

DOI

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8 August 2017

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8 August 2017

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