Enhancing antitumor efficacy of chimeric antigen receptor T cells through constitutive CD40L expression. (Q35399334)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25582824%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Enhancing antitumor efficacy of chimeric antigen receptor T cells through constitutive CD40L expression (English)

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27 February 2020

7

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27 February 2020

author name string

Kevin J Curran

1

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27 February 2020

Beatrijs A Seinstra

2

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27 February 2020

Yan Nikhamin

3

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27 February 2020

Raymond Yeh

4

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27 February 2020

Yelena Usachenko

5

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27 February 2020

Dayenne G van Leeuwen

6

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27 February 2020

Hollie J Pegram

8

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27 February 2020

Renier J Brentjens

9

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27 February 2020

publication date

13 January 2015

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27 February 2020

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27 February 2020

volume

23

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27 February 2020

issue

4

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27 February 2020

page(s)

769-778

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Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

27 February 2020

cites work

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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

27 July 2018

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CD40L expression permits CD8+ T cells to execute immunologic helper functions

27 July 2018

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

27 July 2018

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

27 July 2018

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Upregulation of adhesion molecules on leukemia targets improves the efficacy of cytotoxic T cells transduced with chimeric anti-CD19 receptor

27 July 2018

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Agonistic CD40 antibodies and cancer therapy

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The role of B7 family molecules in hematologic malignancy

27 July 2018

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27 July 2018

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27 July 2018

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Chimeric antigen receptors for T cell immunotherapy: current understanding and future directions

27 July 2018

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Inducible apoptosis as a safety switch for adoptive cell therapy

27 July 2018

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Cutting edge: CD40-CD40 ligand pathway plays a critical CD8-intrinsic and -extrinsic role during rescue of exhausted CD8 T cells

27 July 2018

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Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias

27 July 2018

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

27 July 2018

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

27 July 2018

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Natural innate and adaptive immunity to cancer

27 July 2018

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Efficient human hematopoietic cell transduction using RD114- and GALV-pseudotyped retroviral vectors produced in suspension and serum-free media.

27 July 2018

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Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase

27 July 2018

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27 July 2018

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Differential CD52 expression by distinct myeloid dendritic cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation

27 July 2018

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The CD40/CD154 receptor/ligand dyad

27 July 2018

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CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia

27 July 2018

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Cancer patient T cells genetically targeted to prostate-specific membrane antigen specifically lyse prostate cancer cells and release cytokines in response to prostate-specific membrane antigen

27 July 2018

1 reference

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The critical role of CD40/CD40L in the CD4-dependent generation of CD8+ T cell immunity

27 July 2018

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CD40 is a prognostic marker in primary cutaneous malignant melanoma.

27 July 2018

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

27 July 2018

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CD4+ T-cell induction of Fas-mediated apoptosis in Burkitt's lymphoma B cells

27 July 2018

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Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells

27 July 2018

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Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity

27 July 2018

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Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

27 July 2018

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27 July 2018

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Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells

27 July 2018

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27 July 2018

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Activation of tolerogenic dendritic cells in the tumor draining lymph nodes by CD8+ T cells engineered to express CD40 ligand

27 July 2018

1 reference

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1 reference

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26 September 2018

1 reference

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1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

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26 September 2018

1 reference

12 December 2020

CD40 is functionally expressed on human breast carcinomas: variable inducibility by cytokines and enhancement of Fas-mediated apoptosis

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12 December 2020

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CD40 preferentially costimulates activation of CD4+ T lymphocytes

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A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory

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12 December 2020

Identifiers

DOI

10.1038/MT.2015.4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25582824%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25582824%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference