The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes. (Q35395268)

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8 February 2020

title

The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes (English)

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8 February 2020

1

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Simon Schenk

7

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8 February 2020

author name string

Micah Y Belew

2

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8 February 2020

Ashleigh Evans

3

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8 February 2020

Don Pham

4

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8 February 2020

Itwinder Sivia

5

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8 February 2020

Ai Chen

6

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Keith Baar

8

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publication date

27 July 2011

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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

8 February 2020

published in

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volume

301

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issue

4

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8 February 2020

page(s)

R864-72

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Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes

8 February 2020

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Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria

27 July 2018

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Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria

27 July 2018

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The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells

27 July 2018

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Control of mitochondrial biogenesis during myogenesis

27 July 2018

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Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators

27 July 2018

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Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation

27 July 2018

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

27 July 2018

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Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

27 July 2018

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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

27 July 2018

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Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor

27 July 2018

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27 July 2018

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Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

27 July 2018

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Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c.

27 July 2018

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27 July 2018

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27 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21795630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21795630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21795630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPREGU.00232.2011

1 reference

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8 February 2020

1 reference

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8 February 2020

PubMed publication ID

21795630

1 reference