The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. (Q35306259)

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English	The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses.	scientific article

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25 February 2020

The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses (English)

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Kuzhuvelil B Harikumar

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Sarah Spiegel

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Carole A Oskeritzian

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Nitai C Hait

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Piper Wedman

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Alena Chumanevich

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Elizabeth M Kolawole

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Megan M Price

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Yves T Falanga

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John J Ryan

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Sheldon Milstien

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Roger Sabbadini

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13 December 2014

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The Journal of Allergy and Clinical Immunology

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1008-18.e1

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11 June 2022

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Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

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Interrogation of sphingosine-1-phosphate receptor 2 function in vivo reveals a prominent role in the recovery from IgE and IgG-mediated anaphylaxis with minimal effect on its onset

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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.

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A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma

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IgE and mast cells in allergic disease

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Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness

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Pathophysiology of allergic inflammation

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12 July 2018

Local inactivation of sphingosine 1-phosphate in lymph nodes induces lymphopenia

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Sphingosine-1-phosphate aggravates antigen-induced airway inflammation in mice

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STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

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Modulation of chemokines and allergic airway inflammation by selective local sphingosine-1-phosphate receptor 1 agonism in lungs

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Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.

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Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

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Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model

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Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions

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Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN

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Role of ABCC1 in export of sphingosine-1-phosphate from mast cells

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Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

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1 reference

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Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.JACI.2014.10.044

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25 February 2020

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25 February 2020

1 reference

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25 February 2020

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