Extracellular Hsp90 serves as a co-factor for NF-κB activation and cellular pathogenesis induced by an oncogenic herpesvirus. (Q35298119)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21994906%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Extracellular Hsp90 serves as a co-factor for NF-κB activation and cellular pathogenesis induced by an oncogenic herpesvirus (English)

1 reference

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14 February 2020

0 references

Michael R Defee

1

1 reference

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14 February 2020

Zhiqiang Qin

2

1 reference

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14 February 2020

Lu Dai

3

1 reference

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14 February 2020

Bryan P Toole

4

1 reference

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14 February 2020

Jennifer S Isaacs

5

1 reference

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14 February 2020

Chris H Parsons

6

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14 February 2020

publication date

27 April 2011

1 reference

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American Journal of Cancer Research

14 February 2020

published in

1 reference

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14 February 2020

volume

1

1 reference

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14 February 2020

issue

5

1 reference

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14 February 2020

page(s)

687-700

1 reference

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Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.

14 February 2020

cites work

1 reference

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Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV.

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Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirus

27 July 2018

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TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor

27 July 2018

1 reference

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The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy

27 July 2018

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KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia

27 July 2018

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A systems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation

27 July 2018

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Targeting cancer with small molecule kinase inhibitors

27 July 2018

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17-Allylamino-17-demethoxygeldanamycin down-regulates hyaluronic acid-induced glioma invasion by blocking matrix metalloproteinase-9 secretion

27 July 2018

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Kaposi sarcoma in transplantation

27 July 2018

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Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-kappaB-dependent pathway

27 July 2018

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NF-kappaB in the pathogenesis and treatment of multiple myeloma

27 July 2018

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Persistent Kaposi sarcoma in the era of highly active antiretroviral therapy: characterizing the predictors of clinical response

27 July 2018

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Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression

27 July 2018

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More on HIV-associated Kaposi's sarcoma

27 July 2018

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A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

27 July 2018

1 reference

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Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways

27 July 2018

1 reference

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Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis

27 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation

27 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.

27 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases

27 July 2018

1 reference

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Role of activated nuclear factor-kappaB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck

27 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression

27 July 2018

1 reference

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Systemic treatment of AIDS-related Kaposi sarcoma: current status and perspectives

27 July 2018

1 reference

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Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease

27 July 2018

1 reference

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Identification and characterization of the Orf49 protein of Kaposi's sarcoma-associated herpesvirus

27 July 2018

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Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways

27 July 2018

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Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

27 July 2018

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27 July 2018

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Inhibition of nuclear factor kappaB activity by viral interferon regulatory factor 3 of Kaposi's sarcoma-associated herpesvirus.

27 July 2018

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Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

27 July 2018

1 reference

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Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases

27 July 2018

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Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein

27 July 2018

1 reference

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Clinical presentations and standard therapy of AIDS-associated Kaposi's sarcoma

27 July 2018

1 reference

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Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.

27 July 2018

1 reference

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JlpA of Campylobacter jejuni interacts with surface-exposed heat shock protein 90alpha and triggers signalling pathways leading to the activation of NF-kappaB and p38 MAP kinase in epithelial cells

27 July 2018

1 reference

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Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.

27 July 2018

1 reference

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Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kappa B and induces proinflammatory cytokine and chemokine production via a C-terminal signaling determinant

27 July 2018

1 reference

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The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B.

27 July 2018

1 reference

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The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha

27 July 2018

1 reference

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

27 July 2018

1 reference

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Implication of TNF receptor-I-mediated extracellular signal-regulated kinases 1 and 2 (ERK1/2) activation in growth of AIDS-associated Kaposi's sarcoma cells: a possible role of a novel death domain protein MADD in TNF-alpha-induced ERK1/2 activatio

27 July 2018

1 reference

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Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development

27 July 2018

1 reference

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NF-kappa B: ten years after

27 July 2018

1 reference

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

27 July 2018

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

27 July 2018

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease

27 July 2018

1 reference

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Spindle cells from AIDS-associated Kaposi's sarcoma lesions express telomerase activity that is enhanced by Kaposi's sarcoma progression factors.

27 July 2018

1 reference

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A retrospective analysis of AIDS-associated Kaposi's sarcoma in patients with undetectable HIV viral loads and CD4 counts greater than 300 cells/mm(3).

26 September 2018

1 reference

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Kaposi's sarcoma virally encoded, G-protein-coupled receptor: a paradigm for paracrine transformation.

26 September 2018

1 reference

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TNF induction of jagged-1 in endothelial cells is NFkappaB-dependent

26 September 2018

1 reference

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Extracellular heat shock protein 90 induces interleukin-8 in vascular smooth muscle cells

26 September 2018

1 reference

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Cancer risk in people infected with human immunodeficiency virus in the United States

26 September 2018

1 reference

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An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia.

26 September 2018

1 reference

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Kaposi's sarcoma of the recto sigmoid colon in a patient with HIV infection and a high CD4 count

26 September 2018

1 reference

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Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing

26 September 2018

1 reference

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Emerging targets and novel strategies in the treatment of AIDS-related Kaposi's sarcoma: bidirectional translational science

26 September 2018

1 reference

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Modulation of Kaposi's sarcoma-associated herpesvirus infection and replication by MEK/ERK, JNK, and p38 multiple mitogen-activated protein kinase pathways during primary infection

26 September 2018

1 reference

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ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target cells are essential for expression of viral genes and for establishment of infection

26 September 2018

1 reference

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Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus

26 September 2018

1 reference

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Sirolimus for Kaposi's sarcoma in renal-transplant recipients

26 September 2018

1 reference

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Imatinib-induced regression of AIDS-related Kaposi's sarcoma

26 September 2018

1 reference

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KSHV vFLIP binds to IKK-gamma to activate IKK.

26 September 2018

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Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

26 September 2018

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Interleukin-8 and growth-regulated oncogene alpha mediate angiogenesis in Kaposi's sarcoma

26 September 2018

1 reference

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Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells.

26 September 2018

1 reference

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Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

26 September 2018

1 reference

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Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-kappaB activation

26 September 2018

1 reference

12 December 2020

HIV-associated Kaposi's sarcoma with a high CD4 count and a low viral load

1 reference

12 December 2020

Inflammatory cytokines induce endothelial cells to produce and release basic fibroblast growth factor and to promote Kaposi's sarcoma-like lesions in nude mice

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12 December 2020

NF-kappaB in carcinoma therapy and prevention

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12 December 2020

A Phase I Study of 17-Allylamino-17-Demethoxygeldanamycin Combined with Paclitaxel in Patients with Advanced Solid Malignancies

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12 December 2020

Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21994906%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

21994906

1 reference