CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease. (Q35286992)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease (English)

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2 February 2020

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2

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2 February 2020

Valérie Vingtdeux

3

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2 February 2020

Philippe Marambaud

13

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2 February 2020

10

Julien Chapuis

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2 February 2020

author name string

Jeremy Koppel

1

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2 February 2020

Ute Dreses-Werringloer

4

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2 February 2020

Michael Ewers

5

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2 February 2020

Marc L Gordon

8

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2 February 2020

Erica Christen

9

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2 February 2020

Blaine S Greenwald

11

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2 February 2020

Peter Davies

12

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2 February 2020

Dan Rujescu

6

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2 February 2020

Harald Hampel

7

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2 February 2020

language of work or name

English

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publication date

24 May 2011

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2 February 2020

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2 February 2020

volume

17

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2 February 2020

issue

9-10

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2 February 2020

page(s)

974-979

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https://scigraph.springernature.com/pub.10.2119/molmed.2011.00154

2 February 2020

exact match

0 references

cites work

Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

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The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

27 July 2018

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Validating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levels

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CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid

27 July 2018

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Mitochondria sense with different kinetics the calcium entering into HeLa cells through calcium channels CALHM1 and mutated P86L-CALHM1.

27 July 2018

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

27 July 2018

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

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CALHM1 polymorphism is not associated with late-onset Alzheimer disease

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No association between CALHM1 variation and risk of Alzheimer disease

27 July 2018

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Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid.

27 July 2018

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Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta

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A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk

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27 July 2018

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27 July 2018

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Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

27 July 2018

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Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Alzheimer's disease: genes, proteins, and therapy

27 July 2018

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Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.

27 July 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

27 July 2018

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Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.

27 July 2018

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Revising the definition of Alzheimer's disease: a new lexicon.

26 September 2018

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Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study

26 September 2018

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Calcium signaling and amyloid toxicity in Alzheimer disease

26 September 2018

1 reference

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Lack of implication for CALHM1 P86L common variation in Italian patients with early and late onset Alzheimer's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

CALHM1 P86L polymorphism is associated with late-onset Alzheimer's disease in a recessive model.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

CALHM1 P86L polymorphism is a risk factor for Alzheimer's disease in the Chinese population

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

No association between CALHM1 and Alzheimer's disease risk

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Genetic heterogeneity of Alzheimer's disease: complexity and advances

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation.

26 September 2018

1 reference

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

26 September 2018

1 reference

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Neuropathologic substrate of mild cognitive impairment.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Value of CSF beta-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188873

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21629967

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2119/MOLMED.2011.00154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629967%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21629967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference