Extracellular signalling molecules in the ischaemic/reperfused heart - druggable and translatable for cardioprotection? (Q35286339)

7 August 2017

1 reference

title

Extracellular signalling molecules in the ischaemic/reperfused heart - druggable and translatable for cardioprotection? (English)

1 reference

7 August 2017

P Kleinbongard

1

1 reference

PubMed ID

25204973

7 August 2017

G Heusch

series ordinal

2

1 reference

PubMed ID

25204973

7 August 2017

language of work or name

English

0 references

publication date

24 November 2014

1 reference

British Journal of Pharmacology

7 August 2017

1 reference

7 August 2017

172

1 reference

7 August 2017

2010-2025

1 reference

7 August 2017

8

1 reference

Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioning

7 August 2017

1 reference

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Cardiovascular remodelling in coronary artery disease and heart failure

27 July 2018

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Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning

27 July 2018

1 reference

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The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

27 July 2018

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The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors

27 July 2018

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The Concise Guide to PHARMACOLOGY 2013/14: ion channels

27 July 2018

1 reference

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

27 July 2018

1 reference

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The effect of cyclosporin-A on peri-operative myocardial injury in adult patients undergoing coronary artery bypass graft surgery: a randomised controlled clinical trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Infarct size reduction by cyclosporine A at reperfusion involves inhibition of the mitochondrial permeability transition pore but does not improve mitochondrial respiration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

27 July 2018

1 reference

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Improved long-term clinical outcomes in patients with ST-elevation myocardial infarction undergoing remote ischaemic conditioning as an adjunct to primary percutaneous coronary intervention

27 July 2018

1 reference

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Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNI

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Current state of clinical translation of cardioprotective agents for acute myocardial infarction

27 July 2018

1 reference

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Remote ischaemic preconditioning down-regulates kinin receptor expression in neutrophils of patients undergoing heart surgery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Remote ischemic preconditioning improves outcome at 6 years after elective percutaneous coronary intervention: the CRISP stent trial long-term follow-up

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Cardioprotection: chances and challenges of its translation to the clinic

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Effect of adenosine-regulating agent acadesine on morbidity and mortality associated with coronary artery bypass grafting: the RED-CABG randomized controlled trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

All preconditioning-related G protein-coupled receptors can be demonstrated in the rabbit cardiomyocyte.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Relation of pre-event use of inhibitors of the renin-angiotensin system with myocardial infarct size in patients presenting with a first ST-segment elevation myocardial infarction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Cyclosporine A at reperfusion reduces infarct size in pigs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

ATL 313, A Selective A(2A) Adenosine Receptor Agonist, Reduces Myocardial Infarct Size in a Rat Ischemia/Reperfusion Model

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine receptors and the heart: role in regulation of coronary blood flow and cardiac electrophysiology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Postconditioning and intermittent bradykinin induced cardioprotection require cyclooxygenase activation and prostacyclin release during reperfusion.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Myocardial reperfusion injury.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Peripheral benzodiazepine receptor-induced myocardial protection is mediated by inhibition of mitochondrial membrane permeabilization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Signaling pathways in ischemic preconditioning

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Cardioprotective actions of peptide hormones in myocardial ischemia.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Pretreatment with intracoronary adenosine reduces the incidence of myonecrosis after non-urgent percutaneous coronary intervention: a prospective randomized study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Role of adenosine as adjunctive therapy in acute myocardial infarction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Opioid-induced preconditioning: recent advances and future perspectives

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Delayed adaptation of the heart to stress: late preconditioning

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Preconditioning protects by inhibiting the mitochondrial permeability transition

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Role of opioids in acute and delayed preconditioning

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Kinin-degrading pathways in the human heart

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Metabolic flux rates of adenosine in the heart

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

The late phase of preconditioning

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Enhanced reduction of myocardial infarct size by combined ACE inhibition and AT(1)-receptor antagonism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Bradykinin mediates cardiac preconditioning at a distance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine with cold blood cardioplegia during coronary revascularization.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

AT1 receptor blockade in experimental myocardial ischemia/reperfusion.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Infarct-size limitation by preconditioning is enhanced by dipyridamole administered before but not after preconditioning: evidence for the role of interstitial adenosine level during preconditioning as a primary determinant of cardioprotection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Beneficial effects of bradykinin on myocardial energy metabolism and infarct size

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Role of bradykinin in myocardial preconditioning.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Captopril in acute myocardial infarction: beneficial effects on infarct size and arrhythmias.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Coronary artery reperfusion. II. Reduction of myocardial infarct size at 1 week after the coronary occlusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Coronary artery reperfusion. I. Early effects on local myocardial function and the extent of myocardial necrosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Editorial: Reduction of myocardial-infarct size

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Does choice of anesthetic agent significantly affect outcome after coronary artery surgery?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Randomized trial of primary anesthetic agents on outcome of coronary artery bypass operations.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Diazepam versus fentanyl for premedication during percutaneous coronary intervention: results from the Myocardial Protection by Fentanyl during Coronary Intervention (PROFIT) Trial.

27 July 2018

1 reference

Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: implications for ischemic preconditioning

21 January 2018

1 reference

Preconditioning delays Ca2+-induced mitochondrial permeability transition

21 January 2018

1 reference

Preconditioning ischemia time determines the degree of glycogen depletion and infarct size reduction in rat hearts

21 January 2018

1 reference

Adenosine A1 agonist at reperfusion trial (AART): results of a three-center, blinded, randomized, controlled experimental infarct study.

21 January 2018

1 reference

Trials, tribulations and speculation! Report from the 7th Biennial Hatter Cardiovascular Institute Workshop.

21 January 2018

1 reference

Preoperative angiotensin-converting enzyme inhibitors protect myocardium from ischemia during coronary artery bypass graft surgery.

21 January 2018

1 reference

The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis.

21 January 2018

1 reference

Cardioprotection: spotlight on PKG.

21 January 2018

1 reference

Adenosine: trigger and mediator of cardioprotection

21 January 2018

1 reference

Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels

21 January 2018

1 reference

Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart.

21 January 2018

1 reference

Mapping preconditioning's signaling pathways: an engineering approach.

21 January 2018

1 reference

B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening

21 January 2018

1 reference

Effect of high-dose intracoronary adenosine administration during primary percutaneous coronary intervention in acute myocardial infarction: a randomized controlled trial

21 January 2018

1 reference

Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion

21 January 2018

1 reference

Endogenous κ-opioid peptide mediates the cardioprotection induced by ischemic postconditioning

21 January 2018

1 reference

Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

21 January 2018

1 reference

Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning

21 January 2018

1 reference

Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial.

21 January 2018

1 reference

Investigating the signal transduction pathways underlying remote ischemic conditioning in the porcine heart.

21 January 2018

1 reference

Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice

21 January 2018

1 reference

Adenosine and maximum coronary vasodilation in humans: myth and misconceptions in the assessment of coronary reserve

21 January 2018

1 reference

Reduction of infarct size by ischaemic post-conditioning in humans: fact or fiction?

21 January 2018

1 reference

Remote conditioning: the future of cardioprotection?

21 January 2018

1 reference

The coronary circulation in cardioprotection: more than just one confounder.

21 January 2018

1 reference

Combined adenosine and lidocaine administration limits myocardial reperfusion injury.

21 January 2018

1 reference

Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by delta-opioid receptor activation

21 January 2018

1 reference

Adenosine instead of supranormal potassium in cardioplegia: it is safe, efficient, and reduces the incidence of postoperative atrial fibrillation. A randomized clinical trial.

21 January 2018

1 reference

Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs.

21 January 2018

1 reference

Postconditioning prevents reperfusion injury by activating delta-opioid receptors

21 January 2018

1 reference

Fentanyl protects the heart against ischaemic injury via opioid receptors, adenosine A1 receptors and KATP channel linked mechanisms in rats

21 January 2018

1 reference

Effect of myocardial protection of intracoronary adenosine and nicorandil injection in patients undergoing non-urgent percutaneous coronary intervention: a randomized controlled trial.

21 January 2018

1 reference

Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials

21 January 2018

1 reference

A randomized, double-blinded, placebo-controlled, dose-ranging study measuring the effect of an adenosine agonist on infarct size reduction in patients undergoing primary percutaneous transluminal coronary angioplasty: the ADMIRE (AmP579 Delivery fo

21 January 2018

1 reference

Effects of intracoronary low-dose enalaprilat as an adjunct to primary percutaneous transluminal coronary angiography in acute myocardial infarction

21 January 2018

1 reference

Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?

21 January 2018

1 reference

The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.

21 January 2018

1 reference

Exenatide reduces final infarct size in patients with ST-segment-elevation myocardial infarction and short-duration of ischemia

21 January 2018

1 reference

Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers are beneficial in normotensive atherosclerotic patients: a collaborative meta-analysis of randomized trials.

21 January 2018

1 reference

Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits

21 January 2018

1 reference

Comparison of S-(+)-ketamine- with sufentanil-based anaesthesia for elective coronary artery bypass graft surgery: effect on troponin T levels

21 January 2018

1 reference

Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals.

21 January 2018

1 reference

Diazoxide postconditioning induces mitochondrial protein S-nitrosylation and a redox-sensitive mitochondrial phosphorylation/translocation of RISK elements: no role for SAFE.

21 January 2018

1 reference

Effect of cyclosporine on reperfusion injury in acute myocardial infarction

21 January 2018

1 reference

Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction).

21 January 2018

1 reference

The diverse molecular mechanisms responsible for the actions of opioids on the cardiovascular system

21 January 2018

1 reference

Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary intervention: enhancement by opioid action

21 January 2018

1 reference

A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).

21 January 2018

1 reference

A meta-analysis reporting effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients without heart failure

21 January 2018

1 reference

Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors

21 January 2018

1 reference

Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection

21 January 2018

1 reference

Ischemic postconditioning in pigs: no causal role for RISK activation.

21 January 2018

1 reference

The effect of preconditioning (ischemic and pharmacological) on myocardial necrosis following coronary artery bypass graft surgery

21 January 2018

1 reference

Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrest.

21 January 2018

1 reference

Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury

21 January 2018

1 reference

Redox balance and cardioprotection.

21 January 2018

1 reference

Influence of ACE inhibition on myocardial damage, the Kallikrein-Kinin system and hemostasis during cardiopulmonary bypass surgery

21 January 2018

1 reference

Quaternary ammonium salt of U50488H, a new κ-opioid receptor agonist, protects rat heart against ischemia/reperfusion injury

21 January 2018

1 reference

The anti-inflammatory effect of bradykinin preconditioning in coronary artery bypass grafting (bradykinin and preconditioning).

21 January 2018

1 reference

Bradykinin preconditioning in coronary artery bypass grafting

21 January 2018

1 reference

Remifentanil reduces the release of biochemical markers of myocardial damage after coronary artery bypass surgery: a randomized trial

21 January 2018

1 reference

Remifentanil post-conditioning attenuates cardiac ischemia-reperfusion injury via kappa or delta opioid receptor activation

21 January 2018

1 reference

Limitation of infarct size in rabbit hearts by the novel adenosine receptor agonist AMP 579 administered at reperfusion.

21 January 2018

1 reference

Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology

21 January 2018

1 reference

Ischemic preconditioning increases the bioavailability of cardiac enkephalins

21 January 2018

1 reference

Evidence that cardioprotection by postconditioning involves preservation of myocardial opioid content and selective opioid receptor activation

21 January 2018

1 reference

Anesthetic cardioprotection in clinical practice from proof-of-concept to clinical applications.

21 January 2018

1 reference

Three hours continuous injection of adenosine improved left ventricular function and infarct size in patients with ST-segment elevation myocardial infarction.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Role of endogenous opioids in ischemic preconditioning but not in short-term hibernation in pigs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Effect of adenosine therapy at reperfusion on myocardial infarct size in dogs.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Cardioprotection provided by adenosine receptor activation is abolished by blockade of the KATP channel.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Effects of ischemic and adenosine preconditioning on interstitial fluid adenosine and myocardial infarct size.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Intracoronary EnalaPrilat to Reduce MICROvascular Damage During Percutaneous Coronary Intervention (ProMicro) study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386978

Postconditioning inhibits mitochondrial permeability transition

26 September 2018

1 reference

12 December 2020

Postconditioning the human heart with adenosine in heart valve replacement surgery

1 reference

12 December 2020

We think we see a pattern emerging here

1 reference

12 December 2020

Effects of preconditioning on myocardial interstitial levels of ATP and its catabolites during regional ischemia and reperfusion in the rat

1 reference

12 December 2020

Postconditioning: old wine in a new bottle?

1 reference

12 December 2020

Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation

1 reference

12 December 2020

No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine

1 reference

12 December 2020

Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart

1 reference

12 December 2020

Ischemic preconditioning in pigs: a graded phenomenon: its relation to adenosine and bradykinin

1 reference

12 December 2020

Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice

1 reference

12 December 2020

High-dose intracoronary adenosine for myocardial salvage in patients with acute ST-segment elevation myocardial infarction

1 reference

12 December 2020

Evaluation of intracoronary adenosine to prevent periprocedural myonecrosis in elective percutaneous coronary intervention (from the PREVENT-ICARUS Trial)

1 reference

12 December 2020

The influence of the time period between preconditioning ischemia and prolonged ischemia on myocardial protection

1 reference

12 December 2020

Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs

1 reference

12 December 2020

Involvement of endogenous adenosine in ischaemic preconditioning in swine

1 reference

12 December 2020

Is adenosine preconditioning truly cardioprotective in coronary artery bypass surgery?

1 reference

12 December 2020

Inhibition of mitochondrial permeability transition pore opening: the Holy Grail of cardioprotection

1 reference

12 December 2020

Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G

1 reference

12 December 2020

Cardioprotection: nitric oxide, protein kinases, and mitochondria

1 reference

12 December 2020

Kallidin- and bradykinin-degrading pathways in human heart: degradation of kallidin by aminopeptidase M-like activity and bradykinin by neutral endopeptidase

1 reference

12 December 2020

New method of intracoronary adenosine injection to prevent microvascular reperfusion injury in patients with acute myocardial infarction undergoing percutaneous coronary intervention

1 reference

12 December 2020

Prevention of ischemic preconditioning only by combined inhibition of protein kinase C and protein tyrosine kinase in pigs

1 reference

12 December 2020

Role of bradykinin in protection of ischemic preconditioning in rabbit hearts

1 reference

12 December 2020

Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction

1 reference

12 December 2020

Identifiers

DOI

10.1111/BPH.12902

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

25204973