Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels. (Q35252601)

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5 March 2020

title

Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels (English)

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5 March 2020

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1

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5 March 2020

author name string

Hideyuki Hatakeyama

2

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5 March 2020

Shinsuke Yuasa

3

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5 March 2020

Tomohisa Seki

4

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5 March 2020

Toru Egashira

5

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5 March 2020

Shugo Tohyama

6

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5 March 2020

Yusuke Kuroda

7

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5 March 2020

Atsushi Tanaka

8

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5 March 2020

Shinichiro Okata

9

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5 March 2020

Hisayuki Hashimoto

10

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5 March 2020

Dai Kusumoto

11

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5 March 2020

Akira Kunitomi

12

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5 March 2020

Makoto Takei

13

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5 March 2020

Shin Kashimura

14

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5 March 2020

Tomoyuki Suzuki

15

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5 March 2020

Gakuto Yozu

16

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5 March 2020

Masaya Shimojima

17

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5 March 2020

Chikaaki Motoda

18

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5 March 2020

Nozomi Hayashiji

19

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5 March 2020

Yuki Saito

20

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5 March 2020

Yu-Ichi Goto

21

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5 March 2020

Keiichi Fukuda

22

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5 March 2020

publication date

20 March 2015

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5 March 2020

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5 March 2020

volume

5

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5 March 2020

page(s)

219-225

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Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes

5 March 2020

cites work

1 reference

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Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.

12 July 2018

1 reference

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The role of mitochondrial DNA mutations and free radicals in disease and ageing

12 July 2018

1 reference

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Induced pluripotent stem cells with a mitochondrial DNA deletion

12 July 2018

1 reference

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Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

12 July 2018

1 reference

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Disease characterization using LQTS-specific induced pluripotent stem cells

12 July 2018

1 reference

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Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus

12 July 2018

1 reference

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Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases

12 July 2018

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Mitochondrial DNA mutations in human disease

12 July 2018

1 reference

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Mitochondrial respiratory rates and activities of respiratory chain complexes correlate linearly with heteroplasmy of deleted mtDNA without threshold and independently of deletion size

12 July 2018

1 reference

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Diagnosis and treatment of childhood mitochondrial diseases

12 July 2018

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Mitochondrial diseases in man and mouse

12 July 2018

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Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

12 July 2018

1 reference

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Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems

12 July 2018

1 reference

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A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

12 July 2018

1 reference

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Respiration-deficient cells are caused by a single point mutation in the mitochondrial tRNA-Leu (UUR) gene in mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS)

12 July 2018

1 reference

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Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy

12 July 2018

1 reference

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Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.

12 July 2018

1 reference

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Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutation

26 September 2018

1 reference

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Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.

26 September 2018

1 reference

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The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

26 September 2018

1 reference

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Oxidative capacity correlates with muscle mutation load in mitochondrial myopathy

26 September 2018

1 reference

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10.1016/J.FOB.2015.03.008

26 September 2018

Identifiers

DOI

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5 March 2020

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5 March 2020

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