Nanorobotic investigation identifies novel visual, structural and functional correlates of autoimmune pathology in a blistering skin disease model. (Q35242526)

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English	Nanorobotic investigation identifies novel visual, structural and functional correlates of autoimmune pathology in a blistering skin disease model.	scientific article

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16 February 2020

Nanorobotic investigation identifies novel visual, structural and functional correlates of autoimmune pathology in a blistering skin disease model (English)

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16 February 2020

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16 February 2020

King Wai Chiu Lai

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16 February 2020

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Kristina Seiffert-Sinha

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16 February 2020

Carmen K Fung

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16 February 2020

Kevin C Patterson

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16 February 2020

Aimee S Payne

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16 February 2020

Ning Xi

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16 February 2020

Animesh A Sinha

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8 September 2014

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16 February 2020

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16 February 2020

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16 February 2020

e106895

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16 February 2020

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16 February 2020

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Creative Commons Attribution 4.0 International

8 September 2014

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Beyond annexin V: fluorescence response of cellular membranes to apoptosis

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p38 MAPK activation is downstream of the loss of intercellular adhesion in pemphigus vulgaris

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Desmosomes in vivo

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Apoptolysis: a novel mechanism of skin blistering in pemphigus vulgaris linking the apoptotic pathways to basal cell shrinkage and suprabasal acantholysis

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Pathogenic epitopes of autoantibodies in pemphigus reside in the amino-terminal adhesive region of desmogleins which are unmasked by proteolytic processing of prosequence.

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Biphasic activation of p38MAPK suggests that apoptosis is a downstream event in pemphigus acantholysis

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Targeting pemphigus autoantibodies through their heavy-chain variable region genes

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12 July 2018

Calcium-independent desmosomes of keratinocytes are hyper-adhesive.

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Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells

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Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle

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12 July 2018

Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies

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Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus

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Pemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteraction

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Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display

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Pemphigus vulgaris autoantibodies induce apoptosis in HaCaT keratinocytes.

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12 July 2018

IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model

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Pemphigus vulgaris and pemphigus foliaceus sera show an inversely graded binding pattern to extracellular regions of desmosomes in different layers of human epidermis

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Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8

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Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease

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12 December 2020

based on heuristic

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10.1371/JOURNAL.PONE.0106895

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16 February 2020

2014PLoSO...9j6895S

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16 February 2020

1 reference

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16 February 2020

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