Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes (Q35234637)

7 August 2017

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes (English)

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7 August 2017

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Sarah O'Meara

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Keiran Raine

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Keiran Raine

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Elli Papaemmanuil

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Elli Papaemmanuil

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Anne Vincent-Salomon

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Jórunn Erla Eyfjörd

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Jórunn Erla Eyfjörd

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Anne-Lise Børresen-Dale

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Anne-Lise Børresen-Dale

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Anthony Fullam

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Sancha Martin

Sancha Martin

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Pablo Roman-Garcia

Pablo Roman-Garcia

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Stephen Gamble

Stephen Gamble

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Young Seok Ju

Young Seok Ju

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Ludmil B. Alexandrov

Ludmil Alexandrov

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Daniel Brewer

Daniel Brewer

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Moritz Gerstung

Moritz Gerstung

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Stian Knappskog

Stian Knappskog

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David C. Wedge

David C Wedge

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Peter Van Loo

Peter Van Loo

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Christine Desmedt

Christine Desmedt

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Ultan McDermott

Ultan McDermott

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Sunil R Lakhani

Sunil R Lakhani

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Tapio Visakorpi

Tapio Visakorpi

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Niccolo Bolli

Niccolo Bolli

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Paul N Span

Paul N Span

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Rosalind Eeles

Rosalind Eeles

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P. Andrew Futreal

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P Andrew Futreal

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Ola Myklebost

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Andrew Menzies

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Serena Nik-Zainal

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Carlos Caldas

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Jon W Teague

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Michael R Stratton

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David Neal

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William B Isaacs

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Inigo Martincorena

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Gunes Gundem

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John Marshall

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Helen R Davies

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Patrick S Tarpey

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Sam Behjati

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John A Foekens

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Christos Sotiriou

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Manasa Ramakrishna

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Adam Shlien

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Christodoulos P Pipinikas

7 August 2017

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Christodoulos P Pipinikas

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7 August 2017

Jose M C Tubio

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7 August 2017

Yilong Li

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Susanna L Cooke

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Marta Tojo

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Jorge Zamora

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Adam P Butler

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Lucy R Yates

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Laura Mudie

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7 August 2017

Claire Hardy

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Stuart McLaren

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Elizabeth Anderson

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7 August 2017

Mark Maddison

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Christopher Foster

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Anne Y Warren

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7 August 2017

Hayley Whitaker

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7 August 2017

Colin Cooper

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Andy G Lynch

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Laura Van't Veer

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Sam Aparicio

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Gilles Thomas

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Andrea L Richardson

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7 August 2017

Marc Van de Vijver

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Gert G Van den Eynden

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7 August 2017

Adrienne M Flanagan

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7 August 2017

Sam M Janes

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G Steven Bova

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Peter J Campbell

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7 August 2017

ICGC Breast Cancer Group

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7 August 2017

ICGC Bone Cancer Group

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7 August 2017

ICGC Prostate Cancer Group

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7 August 2017

language of work or name

English

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publication date

1 August 2014

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7 August 2017

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7 August 2017

345

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7 August 2017

1251343

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7 August 2017

6196

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Processed pseudogenes acquired somatically during cancer development

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Discovery and saturation analysis of cancer genes across 21 tumour types

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Punctuated evolution of prostate cancer genomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Transduction-specific ATLAS reveals a cohort of highly active L1 retrotransposons in human populations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Extensive somatic L1 retrotransposition in colorectal tumors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Comprehensive genomic characterization of squamous cell lung cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

An integrated encyclopedia of DNA elements in the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

The origin and evolution of mutations in acute myeloid leukemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Comprehensive molecular characterization of human colon and rectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Landscape of somatic retrotransposition in human cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Sequence analysis of mutations and translocations across breast cancer subtypes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Mutational processes molding the genomes of 21 breast cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Somatic retrotransposition alters the genetic landscape of the human brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

L1 retrotransposition in neurons is modulated by MeCP2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Natural mutagenesis of human genomes by endogenous retrotransposons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

LINE-1 retrotransposition activity in human genomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

L1 retrotransposition in human neural progenitor cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Mobile elements: drivers of genome evolution

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Hot L1s account for the bulk of retrotransposition in the human population

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Initial sequencing and analysis of the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Exon shuffling by L1 retrotransposition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Cytosine methylation and the ecology of intragenomic parasites

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Many human L1 elements are capable of retrotransposition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Trans mobilization of genomic DNA as a mechanism for retrotransposon-mediated exon shuffling.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380235

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

26 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

Fast and accurate long-read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

dbRIP: a highly integrated database of retrotransposon insertion polymorphisms in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

A comprehensive map of mobile element insertion polymorphisms in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

Pebble and rock band: heuristic resolution of repeats and scaffolding in the velvet short-read de novo assembler

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

Paired-end mapping reveals extensive structural variation in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

MethPrimer: designing primers for methylation PCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

Fast gapped-read alignment with Bowtie 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1251343

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1251343

1 reference

7 August 2017

1 reference

7 August 2017

1 reference