Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways (Q35230437)

7 August 2017

Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways (English)

1 reference

7 August 2017

Rhian M Daniel

2

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Adam S. Butterworth

object named as

Adam S Butterworth

3

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Stephen Burgess

object named as

Stephen Burgess

1

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author name string

Simon G Thompson

4

1 reference

PubMed ID

25150977

7 August 2017

EPIC-InterAct Consortium

5

1 reference

7 August 2017

22 August 2014

1 reference

International Journal of Epidemiology

7 August 2017

1 reference

7 August 2017

44

1 reference

7 August 2017

2

1 reference

7 August 2017

484-495

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Commentary on "Mediation analysis without sequential ignorability: Using baseline covariates interacted with random assignment as instrumental variables" by Dylan Small.

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Identification of natural direct effects when a confounder of the mediator is directly affected by exposure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Use of Mendelian randomisation to assess potential benefit of clinical intervention

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Is epidemiology ready for epigenetics?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Avoiding bias from weak instruments in Mendelian randomization studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Inferring causal phenotype networks using structural equation models

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Odds ratios for mediation analysis for a dichotomous outcome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Usefulness of Mendelian randomization in observational epidemiology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Estimating direct effects in cohort and case-control studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Mediation and moderation of treatment effects in randomised controlled trials of complex interventions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Marginal Structural Models for the Estimation of Direct and Indirect Effects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Mendelian randomization as an instrumental variable approach to causal inference

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Instruments for causal inference: an epidemiologist's dream?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Estimation of direct causal effects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

An integrative genomics approach to infer causal associations between gene expression and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Mendelian randomization: prospects, potentials, and limitations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

An introduction to instrumental variables for epidemiologists.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Identifiability and exchangeability for direct and indirect effects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Use of allele scores as instrumental variables for Mendelian randomization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Identifying the odds ratio estimated by a two-stage instrumental variable analysis with a logistic regression model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Improving bias and coverage in instrumental variable analysis with weak instruments for continuous and binary outcomes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Random allocation in observational data: how small but robust effects could facilitate hypothesis-free causal inference

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Bias in causal estimates from Mendelian randomization studies with weak instruments

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Bias formulas for sensitivity analysis for direct and indirect effects

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Instrumental variables: application and limitations.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Genetical genomics: the added value from segregation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469795

Identification, Inference and Sensitivity Analysis for Causal Mediation Effects

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYU176

Bayesian measures of model complexity and fit

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYU176

Estimation of controlled direct effects

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYU176

21 January 2018

Identifiers

DOI

10.1093/IJE/DYU176

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

25150977