GLUT1 enhances mTOR activity independently of TSC2 and AMPK. (Q35216825)

7 August 2017

GLUT1 enhances mTOR activity independently of TSC2 and AMPK. (English)

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7 August 2017

Carolyn L Buller

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7 August 2017

Charles W Heilig

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2

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7 August 2017

Frank C Brosius

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3

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7 August 2017

25 May 2011

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American Journal of Physiology - Renal Physiology

7 August 2017

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7 August 2017

301

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7 August 2017

3

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7 August 2017

F588-96

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describes a project that uses

7 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3174561/fullTextXML

inferred from PubMed Central ID database lookup

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Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis

13 July 2018

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GLUT1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular smooth muscle cells

13 July 2018

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Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

13 July 2018

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A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression

13 July 2018

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Mechanical forces in diabetic kidney disease: a trigger for impaired glucose metabolism

13 July 2018

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Role for GLUT1 in diabetic glomerulosclerosis

13 July 2018

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Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy

13 July 2018

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The expanding TOR signaling network

13 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

13 July 2018

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13 July 2018

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13 July 2018

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Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.

13 July 2018

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TSC2 mediates cellular energy response to control cell growth and survival

13 July 2018

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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

13 July 2018

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Glucose uptake and adenoviral mediated GLUT1 infection decrease hypoxia-induced HIF-1alpha levels in cardiac myocytes

13 July 2018

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

13 July 2018

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Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes

13 July 2018

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D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy

13 July 2018

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13 July 2018

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Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

13 July 2018

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Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype

13 July 2018

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Increased glucose uptake and metabolism in mesangial cells overexpressing glucose transporter 1 increases interleukin-6 and vascular endothelial growth factor production: role of AP-1 and HIF-1alpha.

13 July 2018

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Role of TGF-beta/GLUT1 axis in susceptibility vs resistance to diabetic glomerulopathy in the Milan rat model.

26 September 2018

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Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

26 September 2018

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Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

26 September 2018

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Evidence for a novel TGF-beta1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters

26 September 2018

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Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

26 September 2018

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Increased renal GLUT1 abundance and urinary TGF-beta 1 in streptozotocin-induced diabetic rats: implications for the development of nephropathy complicating diabetes

26 September 2018

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Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression

26 September 2018

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GLUT1 and TGF-beta: the link between hyperglycaemia and diabetic nephropathy

26 September 2018

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Cloning of rat homologue of podocin: expression in proteinuric states and in developing glomeruli

26 September 2018

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Crossref

https://api.crossref.org/works/10.1152%2FAJPRENAL.00472.2010

Progression of diabetic nephropathy

21 January 2018

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12 December 2020

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

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12 December 2020

Mouse models of diabetic nephropathy

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12 December 2020

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

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12 December 2020

Rapamycin prevents early steps of the development of diabetic nephropathy in rats

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12 December 2020

10.1152/AJPRENAL.00472.2010

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference