Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria (Q35216393)

7 August 2017

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title

Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria (English)

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7 August 2017

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Georges E Grau

2

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author name string

Nicholas H Hunt

series ordinal

1

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7 August 2017

1 September 2003

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7 August 2017

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7 August 2017

24

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7 August 2017

491-499

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7 August 2017

9

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Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis

7 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Early activation of microglia in the pathogenesis of fatal murine cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Compromised blood-nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Widespread expression of MRP8 and MRP14 in human cerebral malaria by microglial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cerebral malaria. A disseminated vasculomyelinopathy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Axonal injury in cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Breakdown of the blood-brain barrier in murine cerebral malaria.

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

The cytokine theory of human cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Late administration of monoclonal antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Role of ICAM-1 (CD54) in the development of murine cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Prognostic value of thrombocytopenia in African children with falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Involvement of IFN-gamma receptor-medicated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Interleukin-10 inhibits tumor necrosis factor production but not antigen-specific lymphoproliferation in acute Plasmodium falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cytokine profiles for human V gamma 9+ T cells stimulated by Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cellular basis of early cytokine response to Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Tumor necrosis factor and disease severity in children with falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Tumor necrosis factor and severe malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Tumour necrosis factor, interleukin-6, and malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Soluble tumor necrosis factor receptors correlate with parasitemia and disease severity in human malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Requirement for tumor necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Pentoxifylline prevents murine cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Plasma interleukin-10:Tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complications.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Strong association of a tumor necrosis factor-alpha promoter allele with cerebral malaria in Myanmar.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Lack of association of -308A/G TNFA promoter and 196R/M TNFR2 polymorphisms with disease severity in Thai adult malaria patients

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

TNF and Plasmodium berghei ANKA-induced cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cytokine expression in the brain in human cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Increased lymphotoxin in human malarial serum, and the ability of this cytokine to increase plasma interleukin-6 and cause hypoglycaemia in mice: implications for malarial pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Production of tumor necrosis factors alpha and beta by human mononuclear leukocytes stimulated with mitogens, bacteria, and malarial parasites

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Interleukin-10 modulates susceptibility in experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Endogenous interleukin-10 modulates proinflammatory response in Plasmodium falciparum malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

The prognostic and pathophysiologic role of pro- and antiinflammatory cytokines in severe malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Interleukin-10 and the interleukin-10 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

CCR5 deficiency decreases susceptibility to experimental cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Fas and perforin contribute to the pathogenesis of murine cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Transforming growth factor beta production is inversely correlated with severity of murine malaria infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Identification of two cerebral malaria resistance loci using an inbred wild-derived mouse strain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Blood-brain barrier function in cerebral malaria and CNS infections in Vietnam

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Differential cellular accumulation of transforming growth factor-beta1, -beta2, and -beta3 in brains of patients who died with cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Isolating vessels from the mouse brain for gene expression analysis using laser capture microdissection.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Pathophysiological and prognostic significance of cerebrospinal-fluid lactate in cerebral malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Is ischemia involved in the pathogenesis of murine cerebral malaria?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

1H-magnetic resonance spectroscopy-determined cerebral lactate and poor neurological outcomes in children with central nervous system disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: role of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Bench-to-bedside review: Cytopathic hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

Cellular stress and injury responses in the brains of adult Vietnamese patients with fatal Plasmodium falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900229-1

7 January 2021

10.1016/S1471-4906(03)00229-1

Identifiers

DOI

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7 August 2017

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PubMed ID

12967673