Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013 (Q35215022)

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English	Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013	scientific article

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scholarly article

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11 March 2020

Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013 (English)

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11 March 2020

Aspergillus fumigatus

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Oliver A Cornely

4

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11 March 2020

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11 March 2020

Dieter Buchheidt

15

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11 March 2020

Cornelia Lass-Florl

7

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Cornelia Lass-Flörl

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Birgit Spiess

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11 March 2020

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Patricia Postina

2

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11 March 2020

Mark Reinwald

3

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11 March 2020

Peter-Michael Rath

8

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11 March 2020

Jörg Steinmann

9

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11 March 2020

Thomas Miethke

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11 March 2020

Melchior Lauten

11

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11 March 2020

Silke Will

12

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11 March 2020

Natalia Merker

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11 March 2020

Wolf-Karsten Hofmann

14

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29 July 2014

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11 March 2020

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11 March 2020

9

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11 March 2020

7

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11 March 2020

e103113

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11 March 2020

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Creative Commons Attribution 4.0 International

29 July 2014

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April 2022 Public Data File from Crossref

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0 references

Aspergillus PCR-based investigation of fresh tissue and effusion samples in patients with suspected invasive Aspergillosis enhances diagnostic capabilities

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cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany.

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Diagnostic performance of an Aspergillus-specific nested PCR assay in cerebrospinal fluid samples of immunocompromised patients for detection of central nervous system aspergillosis

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13 July 2018

Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR₃₄/L98H mutations in the cyp51A gene in India

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Azole-resistant invasive aspergillosis in a patient with acute myeloid leukaemia in Germany.

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First reported case of azole-resistant aspergillus fumigatus due to the TR/L98H mutation in Germany

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13 July 2018

Development of novel PCR assays to detect azole resistance-mediating mutations of the Aspergillus fumigatus cyp51A gene in primary clinical samples from neutropenic patients.

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Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus

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Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009.

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Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene

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13 July 2018

Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.

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High-frequency triazole resistance found In nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease

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Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.

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Rapid diagnosis of azole-resistant aspergillosis by direct PCR using tissue specimens

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Azole-resistance in Aspergillus: proposed nomenclature and breakpoints

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Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

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A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

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Breakthrough pulmonary Aspergillus fumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia

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Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles

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Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies.

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Novel mixed-format real-time PCR assay to detect mutations conferring resistance to triazoles in Aspergillus fumigatus and prevalence of multi-triazole resistance among clinical isolates in the Netherlands.

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High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis.

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10.1371/JOURNAL.PONE.0103113

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11 March 2020

2014PLoSO...9j3113S

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11 March 2020

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11 March 2020

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