Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid (Q35210180)

7 August 2017

1 reference

title

Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid (English)

1 reference

7 August 2017

0 references

María-Salud García-Ayllón

1

1 reference

7 August 2017

David H Small

2

1 reference

7 August 2017

Jesús Avila

3

1 reference

7 August 2017

Javier Sáez-Valero

4

1 reference

7 August 2017

13 September 2011

1 reference

Frontiers in Molecular Neuroscience

7 August 2017

1 reference

7 August 2017

4

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7 August 2017

22

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Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice.

7 August 2017

1 reference

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Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells

28 July 2018

1 reference

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Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo

28 July 2018

1 reference

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Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons

28 July 2018

1 reference

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Altered levels of acetylcholinesterase in Alzheimer plasma

28 July 2018

1 reference

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Effects of donepezil on amyloid-beta and synapse density in the Tg2576 mouse model of Alzheimer's disease

28 July 2018

1 reference

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Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer's disease.

28 July 2018

1 reference

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N-acetylcholinesterase-induced apoptosis in Alzheimer's disease

28 July 2018

1 reference

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Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation.

28 July 2018

1 reference

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Non-hydrolytic functions of acetylcholinesterase. The significance of C-terminal peptides.

28 July 2018

1 reference

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Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity

28 July 2018

1 reference

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The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice.

28 July 2018

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28 July 2018

1 reference

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Effects of huperzine A on amyloid precursor protein processing and beta-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells

28 July 2018

1 reference

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Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials

28 July 2018

1 reference

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The readthrough variant of acetylcholinesterase remains very minor after heat shock, organophosphate inhibition and stress, in cell culture and in vivo

28 July 2018

1 reference

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Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology

28 July 2018

1 reference

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Cholinesterase inhibitors influence APP metabolism in Alzheimer disease patients.

28 July 2018

1 reference

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Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines.

28 July 2018

1 reference

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History of lectins: from hemagglutinins to biological recognition molecules

28 July 2018

1 reference

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The cholinergic innervation of the human cerebral cortex

28 July 2018

1 reference

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The role of acetylcholinesterase in the pathogenesis of Alzheimer's disease

28 July 2018

1 reference

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Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease

28 July 2018

1 reference

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Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

28 July 2018

1 reference

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The origin of the molecular diversity and functional anchoring of cholinesterases

28 July 2018

1 reference

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PRiMA: the membrane anchor of acetylcholinesterase in the brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase in Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease

28 July 2018

1 reference

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Molecular genetics of Alzheimer's disease.

28 July 2018

1 reference

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Glycosylation differences between the normal and pathogenic prion protein isoforms

28 July 2018

1 reference

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Structural roles of acetylcholinesterase variants in biology and pathology

28 July 2018

1 reference

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Cholinesterases in neural development: new findings and toxicologic implications

28 July 2018

1 reference

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The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling

28 July 2018

1 reference

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Acute stress facilitates long-lasting changes in cholinergic gene expression

28 July 2018

1 reference

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The cholinergic system in Alzheimer's disease

28 July 2018

1 reference

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Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease

28 July 2018

1 reference

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Existence of an inactive pool of acetylcholinesterase in chicken brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

The cholinesterases: from genes to proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Molecular forms of acetylcholinesterase in senile dementia of Alzheimer type: selective loss of the intermediate (10S) form

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Molecular forms and solubility of acetylcholinesterase during the embryonic development of rat and human brain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Assembly of monomeric acetylcholinesterase into tetrameric and asymmetric forms.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Neocortical cholinergic enzyme and receptor activities in the human fetal brain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Cholinesterases within neurofibrillary tangles related to age and Alzheimer's disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Molecular forms of butyrylcholinesterase in the human neocortex during development and degeneration of the cortical cholinergic system.

28 July 2018

1 reference

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

28 July 2018

1 reference

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

28 July 2018

1 reference

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Acetylcholinesterase in Huntington's and Alzheimer's diseases: simultaneous enzyme assay and immunoassay of multiple brain regions

28 July 2018

1 reference

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

28 July 2018

1 reference

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Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease.

28 July 2018

1 reference

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Molecular forms of acetylcholinesterases in Alzheimer's disease

28 July 2018

1 reference

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Shifting patterns of cortical cholinesterases in Alzheimer's disease: implications for treatment, diagnosis, and pathogenesis.

28 July 2018

1 reference

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Senile plaques: staining for acetylcholinesterase and A4 protein: a comparative study in the hippocampus and entorhinal cortex

28 July 2018

1 reference

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Preferential inhibition of acetylcholinesterase molecular forms in rat brain

28 July 2018

1 reference

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Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

28 July 2018

1 reference

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Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Solubilization and physicochemical characterization of rat brain acetylcholinesterase: development and maturation of its molecular forms

28 July 2018

1 reference

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Necropsy evidence of central cholinergic deficits in senile dementia

28 July 2018

1 reference

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Selective loss of central cholinergic neurons in Alzheimer's disease

28 July 2018

1 reference

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Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

APP processing in Alzheimer's disease

26 September 2018

1 reference

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Changes in CSF acetyl- and butyrylcholinesterase activity after long-term treatment with AChE inhibitors in Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase variants in Alzheimer's disease: from neuroprotection to programmed cell death.

26 September 2018

1 reference

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Cholinesterase inhibitors and beyond

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons.

26 September 2018

1 reference

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Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals

26 September 2018

1 reference

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Amyloid-cholinesterase interactions. Implications for Alzheimer's disease

26 September 2018

1 reference

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Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.

26 September 2018

1 reference

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On functions of cholinesterases during embryonic development.

26 September 2018

1 reference

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Changes in the activity and protein levels of CSF acetylcholinesterases in relation to cognitive function of patients with mild Alzheimer's disease following chronic donepezil treatment.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation

26 September 2018

1 reference

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Altered glycosylation of acetylcholinesterase in Creutzfeldt-Jakob disease.

26 September 2018

1 reference

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Cholinesterases: roles in the brain during health and disease.

26 September 2018

1 reference

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Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development.

26 September 2018

1 reference

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Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach

26 September 2018

1 reference

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Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain

26 September 2018

1 reference

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A new and rapid colorimetric determination of acetylcholinesterase activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid beta-peptide.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Effects of acetylcholinesterase inhibitors on the metabolism of amyloid precursor protein in vitro.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase--new roles for an old actor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Excess "read-through" acetylcholinesterase attenuates but the "synaptic" variant intensifies neurodeterioration correlates

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Altered glycosylation pattern of proteins in Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Developmental regulation of mouse brain monomeric acetylcholinesterase.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Effects of cholinesterase inhibitors on the secretion of beta-amyloid precursor protein in cell cultures.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Nonclassical roles of cholinesterases in the embryonic brain and possible links to Alzheimer disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Neurological cholinesterases in the normal brain and in Alzheimer's disease: relationship to plaques, tangles, and patterns of selective vulnerability.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Molecular and cellular biology of cholinesterases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Cholinesterase inhibitors increase secretion of APPs in rat brain cortex.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Slow accumulation of acetylcholinesterase in rat brain during enzyme inhibition by repeated dosing with chlorpyrifos.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Cellular localization of the molecular forms of acetylcholinesterase in rat pheochromocytoma PC12 cells treated with nerve growth factor.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Acetylcholinesterase-rich pyramidal neurons in Alzheimer's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171929

Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine

26 September 2018

1 reference

12 December 2020

Inactive monomeric acetylcholinesterase in the low-salt-soluble extract of the electric organ from Torpedo marmorata

1 reference

12 December 2020

Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system

1 reference

12 December 2020

Tacrine may alter APP-like protein levels in the lumbar CSF of Alzheimer patients

1 reference

12 December 2020

Molecular forms of sucrose extractable and particulate acetylcholinesterase in the developing and adult rat brain

1 reference

12 December 2020

Histochemical observations on cholinesterase activities in the brains of elderly normal and demented (Alzheimer-type) patients

1 reference

12 December 2020

An unusually glycosylated form of acetylcholinesterase is a CSF biomarker for Alzheimer's disease

1 reference

12 December 2020

Biogenesis of acetylcholinesterase molecular forms in muscle. Evidence for a rapidly turning over, catalytically inactive precursor pool

1 reference

12 December 2020

Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNMOL.2011.00022

1 reference

7 August 2017

1 reference

7 August 2017

1 reference