The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. (Q35206874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941395%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

review article

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title

The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release (English)

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7 November 2019

1

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7 November 2019

author name string

Klaus Strebel

series ordinal

2

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7 November 2019

publication date

1 September 2003

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7 November 2019

published in

Microbes and Infection

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7 November 2019

volume

5

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7 November 2019

issue

11

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7 November 2019

page(s)

1029-1039

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Cell-free transmission of Vif mutants of HIV-1

7 November 2019

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Membrane interactions and alignment of structures within the HIV-1 Vpu cytoplasmic domain: effect of phosphorylation of serines 52 and 56

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HIV-1 encoded virus protein U (Vpu) solution structure of the 41-62 hydrophilic region containing the phosphorylated sites Ser52 and Ser56.

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Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein

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Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity

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The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

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Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity

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Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum

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Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

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7 January 2021

Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4

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7 January 2021

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

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Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

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Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors

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7 January 2021

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7 January 2021

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

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Functional role of human immunodeficiency virus type 1 vpu.

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Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein

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Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export

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7 January 2021

Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function

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Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein

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Viral protein U (Vpu)-mediated enhancement of human immunodeficiency virus type 1 particle release depends on the rate of cellular proliferation

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7 January 2021

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

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Simulation of the HIV-1 Vpu transmembrane domain as a pentameric bundle

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Ion channels formed by HIV-1 Vpu: a modelling and simulation study

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Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses

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The Antibody Response to the HIV-1 Specific "Out" (vpu) Protein: Identification of an Immunodominant Epitope and Correlation of Antibody Detectability to Clinical Stages

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Presence of Intact vpu and nef genes in nonpathogenic SHIV is essential for acquisition of pathogenicity of this virus by serial passage in macaques

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Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques

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Identifiers

DOI

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7 November 2019

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